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The primary goal of this randomized clinical trial (RCT) is to evaluate whether Kinesio Taping versus McConnell Taping, when integrated into a standardized hip-knee strengthening and neuromuscular control program, produces significant effects in individuals aged 18-50 with patellofemoral pain syndrome (PFPS).
The main question it aims to answer is: Does Kinesio Taping compared with McConnell Taping when both combined with a standardized hip-knee exercise program, produce different effects on quadriceps neuromuscular activation (VMO-VL sEMG), pain, functional knee pain, and dynamic knee valgus over a 6 week period intervention?
Participants will be divided into three groups for comparison: the control group will receive a structured hip-knee physical therapy exercise program without any taping intervention, Kinesio Taping group with a standardized exercise program, and a McConnell Taping group with a standardized exercise program.
Kinesio Taping and McConnell Taping are commonly used as adjuncts to exercise therapy in the management of patellofemoral pain syndrome. Both techniques have been shown to improve pain and function in the short term; however, evidence directly comparing their long-term effects when combined with a standardized exercise program remains limited. Furthermore, the influence of taping modality on quadriceps muscle activation and lower-limb kinematic patterns during rehabilitation has not been fully established.
Based on this, the investigators hypothesize that both interventions will improve clinical and neuromuscular outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Kinesio Tape Group | Experimental | The subjects will receive Kinesio Taping combined with the structured exercise program. |
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| McConnell Taping Group | Experimental | The subjects will receive McConnell Taping combined with the structured exercise program. |
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| Exercise Only Group | Active Comparator | A standardized hip-knee strengthening and neuromotor training program will be performed for 6 weeks. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Kinesio Taping | Other | Kinesio Taping will be applied to the patellofemoral joint during a 6-week structured hip-knee exercise program. |
|
| Measure | Description | Time Frame |
|---|---|---|
| VMO and VL Muscle Activation Amplitude | Surface electromyography (sEMG) amplitude of the Vastus Medialis Obliquus (VMO) and Vastus Lateralis (VL) muscles recorded during a standardized single-leg squat task. Higher values indicate greater muscle activation. | Baseline and post-intervention (6 weeks). |
| VMO/VL Activation Ratio | Ratio of VMO to VL electromyographic activity during a standardized single-leg squat task. The ideal VMO/VL ratio should be close or equal to 1; a ratio greater than 1 reflects higher VMO activation, while a ratio less than 1 reflects a greater VL activation. | Baseline and post-intervention (6 weeks). |
| VMO Onset Timing | Period from movement initiation to onset of VMO and VL activation, measured using sEMG during a standardized single-leg squat task; measured in ms. | Baseline to post-intervention (6 weeks). |
| VMO-VL Activation Delay | Difference in activation onset timing between the VMO and VL muscles during a standardized single-leg squat task, measured using sEMG; measured in ms. | Baseline to post-intervention (6 weeks). |
| Measure | Description | Time Frame |
|---|---|---|
| Pain Intensity | Task-specific pain intensity measured using the Visual Analogue Scale (VAS), ranging from 0 to 10, where 0 = no pain and 10 = worst imaginable pain; measured during a standardized single-leg squat, reflecting pain experienced during functional loading. | Baseline and post-intervention (6 weeks). |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed El Melhat, PhD | Contact | +201112595022 | ahmed.elmelhat@cu.edu.eg | |
| Mohamad Ibrahim Baayoun, BSc | Contact | +96181852495 | mohdbaa500@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed El Melhat, PhD | Cairo University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| PTOC Beirut Arab University | Recruiting | Beirut | Beirut | 0000 | Lebanon |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40259274 | Result | Jiao H, Tao M, Cui X. Efficacy on pain and knee function of Kinesio taping among patients with patellofemoral pain syndrome: a systematic review and meta-analysis. BMC Musculoskelet Disord. 2025 Apr 21;26(1):388. doi: 10.1186/s12891-025-08627-7. | |
| 26185517 | Result | Chang WD, Chen FC, Lee CL, Lin HY, Lai PT. Effects of Kinesio Taping versus McConnell Taping for Patellofemoral Pain Syndrome: A Systematic Review and Meta-Analysis. Evid Based Complement Alternat Med. 2015;2015:471208. doi: 10.1155/2015/471208. Epub 2015 Jun 21. |
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| McConnell Taping | Other | McConnell Taping will be applied to correct patellar alignment during a 6-week structured hip-knee exercise program. |
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| Exercise Therapy | Other | A standardized hip-knee strengthening and neuromotor training program will be performed for 6 weeks. |
|
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| Functional Knee Pain |
Knee-related symptoms and functional disability assessed using the Kujala Score (AKPS), ranging from 0 to 100, where higher scores indicating better knee function and lower disability. |
| Baseline and post-intervention (6 weeks). |
| Dynamic Knee Valgus | Frontal-plane projection angle in degrees, measured during a standardized single-leg squat to quantify lower-limb movement quality and dynamic knee control under functional load. | Baseline and post intervention (6 weeks). |
| 35954598 | Result | Pereira PM, Baptista JS, Conceicao F, Duarte J, Ferraz J, Costa JT. Patellofemoral Pain Syndrome Risk Associated with Squats: A Systematic Review. Int J Environ Res Public Health. 2022 Jul 28;19(15):9241. doi: 10.3390/ijerph19159241. |
| ID | Term |
|---|---|
| D046788 | Patellofemoral Pain Syndrome |
| ID | Term |
|---|---|
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D015444 | Exercise |
| ID | Term |
|---|---|
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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