the goal of this clinical trial is to compare the effect of vaping vs traditional smoking on non surgical periodontal therapy . the main question it aims to answer is what is the impact of traditional smoking and vaping on periodontal health and how do IL-1B and IL-20 serve as mediators in the inflammatory processes linked to periodontal disease?

the goal of this clinical trial is to compare the effect of vaping vs traditional smoking on non surgical periodontal therapy . the main question it aims to answer is what is the impact of traditional smoking and vaping on periodontal health and how do IL-1B and IL-20 serve as mediators in the inflammatory processes linked to periodontal disease? .A randomized controlled clinical trial will be conducted on patients with periodontitis stage II . participants will be allocated to one of three groups: traditional smokers , vapers and non-smokers . the randomization process will ensure unbiased distribution of participants across the groups . periodontal health will be evaluated through clinical assesment ( probing depth as primary outcome, clinical attachemt level, bleeding on probing and GI ) then cytokine levels (IL-1B , IL-20) will be assessed.

Inclusion Criteria:

• pts aged 20-40 years
• pts with stage II periodontitis
• systemically healthy with no chronic diseases
• no current use of medication
• participants have the same socioeconomic status
• participants must be able to understand and comply with the study protocol and give informed consent

Exclusion Criteria:

• pts with severe systemic diseases
• recent use of immunosuppressants or medications that affect oral health
• history of illicit drug use within the past 12 months
• periodontal surgery or scaling within the last 6 months
• participants in another clinical trial
• vulnerable individuals as children and pregnant

IPD will not be shared to protect participant confidentiality and due to ethical considerations. only summarized and deidentified data will be published