European Multi-Centre Post-Market Registry on Thoracic Endovascular Arch Repair Using Castor™ and Cratos™

ClinicalTrials.gov ID

NCT07668687

Lead Sponsor

Shanghai MicroPort Endovascular MedTech（Group）Co., LtdINDUSTRY

Overall Status

Recruiting

Study Type

Observational

Enrollment

100Estimated

Last Update Posted

Jun 25, 2026Actual

Start Date

Sep 12, 2025Actual

Primary Completion Date

Oct 2028Estimated

Completion Date

Dec 2033Estimated

Official Title

European Multi-Centre Castor™ and Cratos™ Branched Endovascular Arch Repair Registry

Brief Summary

The Castor™ and Cratos™ Branched Aortic Stent Graft Systems are medical devices designed for the minimally invasive endovascular treatment of thoracic aortic pathologies in the descending aorta. The goal of this multi-centre retrospective and prospective observational registry study is to capture the short-, medium- to long-term safety and performance data of how Castor™ and Cratos™ stent-grafts work in real-world settings (everyday medical practice). The aim is to study approximately 100 patients in European hospitals, with competitive enrollment.

Detailed Description

The CEDAR registry is a post-market clinical study with retrospective and prospective enrollment and retrospective and prospective data collection.

• Dissection of Thoracic Aorta
• Dissection of Thoracic Descending Aorta
• Aneurysm of Aorta, Thoracic
• Penetrating Aortic Ulcers (PAUs)
• Intramural Hematoma of the Thoracic Aorta
• Ulcer-like Projection (ULP)

• Implantation with Castor™ stent graft
• Implantation with Cratos™ stent graft

Ages Eligible for Study

Adult (18-64)Older Adult (65+)

Sexes Eligible for Study

All

Accepts Healthy Volunteers

No

Eligibility Criteria

Inclusion Criteria:

• Implantation of a Castor™ or Cratos™ single branch endoprothesis with incorporation of the left subclavian artery
• Age >18 years

Exclusion Criteria:

• Patients allergic to the materials of the device;
• Patients with severe or potentially systemic infections that increase the chance of graft infection;
• Minors and pregnant women;
• Branch for other supra-aortic vessels than the LSA
• Rejection of participation.

Observational Model

Cohort

Time Perspective

Other

Lead Sponsor

Shanghai MicroPort Endovascular MedTech（Group）Co., LtdINDUSTRY

vital@ukmuenster.de00492518351717

daniel.danzer@hopitalvs.ch0041276034124

Susanne.Menz@usz.ch0041432530243

• A Multi-center Trial of Single-Branched Stent Graft System to Treat Aortic Dissection

  NCT01914237

  Unknown statusInterventionalNot ApplicableUpdated Aug 2, 2013
• CRATOS - Evaluation of Cratos™ Branch Stent Graft System in Treatment of Descending Aorta Lesions

  NCT05874206

  RecruitingInterventionalNot ApplicableUpdated Feb 26, 2025
• Evaluation of the Castor Single Branch Stent Graft in Treatment of Acute Aortic Syndrome

  NCT05965453

  RecruitingObservationalUpdated Jul 28, 2023
• Prospective, Multicenter, Single-Arm Study of Aortic Arch Pathology Reconstruction

  NCT07139912

  Not yet recruitingInterventionalNot ApplicableUpdated Aug 24, 2025
• Study on Multibranched Stent Graft System in the Treatment of Thoracoabdominal Aortic Aneurysm

  NCT06478576

  RecruitingInterventionalNot ApplicableUpdated Jul 12, 2024
• Terumo Aortic Global Endovascular Registry

  NCT04246463

  RecruitingObservationalUpdated Mar 13, 2026