Effects of Seed Cycling Capsules on Premenstrual Syndrome Symptoms and Menstrual Cycle Length

Effects of Seed Cycling Capsules on Premenstrual Syndrome Symptoms and Menstrual Cycle Length

This virtual, single-arm clinical trial will evaluate the effects of Seed Cycling Capsules on symptoms associated with premenstrual syndrome (PMS) and menstrual cycle characteristics. Forty female participants aged 18 to 45 years will use the study products daily for two menstrual cycles. Participants will complete questionnaires at baseline, at the end of their period during Cycle 1, and at the end of their period during Cycle 2.

Inclusion Criteria:

• Be female.
• Be 18-45 years of age.
• Have experienced at least five of the following symptoms during the last three menstrual cycles:

Heavy flow Prolonged, shortened, or irregular periods Headaches or migraines Low mood Fatigue Bloating Premenstrual or menstrual cramps Breast tenderness Poor sleep Constipation or diarrhea Weight gain or fluctuations Irritability or anger Sick days or reduced social activity due to menstrual symptoms Hormonal acne

• Be generally healthy.
• Have a menstrual cycle length between 23 and 35 days.
• Track menstrual cycles and be able to predict period dates.
• Be willing to refrain from taking products, medications, or supplements targeting menstrual health during the study.

Exclusion Criteria:

• Use of hormonal contraception.
• Allergy to sesame.
• Chronic conditions that would interfere with study participation, including oncological and psychiatric disorders.
• Pregnant, breastfeeding, or trying to conceive.
• Unwillingness to follow the protocol.
• Menopause or menopausal symptoms.
• Recent or planned invasive medical procedures.
• History of substance abuse.
• Diabetes or other endocrine-related conditions.
• Current or planned participation in another research study.
• Use of hormone-modulating medications or therapies.
• Planned insertion or replacement of an IUD within 12 weeks.
• Diagnosis of endometriosis, polycystic ovary syndrome (PCOS), or adenomyosis.