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After deciding to join this study and signing the informed consent form, participants will undergo the following interventions:
All participants will receive a preoperative assessment (Tp) before surgery. Within five days after transferring from the ICU to the general ward, participants will receive a baseline assessment (T0). After completing seven sessions of myofascial release (MFR), a post-intervention assessment (T1) will be conducted.
Assessments include maximum inspiratory pressure (MIP), maximum expiratory pressure (MEP), pulmonary function tests, mid- and lower-thoracic mobility, surface electromyography (sEMG) to measure diaphragmatic and sternocleidomastoid muscle activity, and pain scores. Pulmonary function tests include forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC ratio, and maximum voluntary ventilation (MVV).
Participants will be randomly assigned to an intervention group or a control group. The intervention group will receive myofascial release therapy in addition to routine physical therapy in the general ward. Routine therapy includes daily physical therapy sessions such as out-of-bed activities, incentive spirometry training (Triflow), and functional exercises. The MFR intervention consists of three steps:
The therapist places both hands on the thoracic outlet, with the index and middle fingers above the clavicle.
One hand is placed on the anterior chest and the other hand parallel on the participant's back.
Both hands are placed on the anterolateral region of the thoracoabdominal diaphragm.
During each step, participants are instructed to take 10 slow, deep breaths and direct airflow toward the therapist's hands. Each session lasts approximately 15 minutes, once daily, for seven sessions.
The control group will receive only routine physical therapy (out-of-bed activities, incentive spirometry, and functional exercises) without additional myofascial release therapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| (Control Group) Arm Title: Control Group - Routine Physical Therapy | Active Comparator | Routine Physical Therapy |
|
| Experimental: (Intervention Group) Arm Title: Myofascial Release + Routine Physical Therapy | Experimental | Experimental: (Intervention Group) Arm Title: Intervention Group - Myofascial Release+Routine Physical Therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| myofascial release+Routine Physical Therapy | Behavioral | Participants in the intervention group will receive seven daily sessions of myofascial release (MFR), approximately 15 minutes each, in addition to routine physical therapy. Routine therapy includes out-of-bed activities, incentive spirometry training (Triflow), and functional exercises. The MFR procedure consists of three steps: Therapist places both hands on the thoracic outlet, with index and middle fingers above the clavicle. One hand is placed on the anterior chest and the other parallel on the participant's back. Both hands are placed on the anterolateral thoracoabdominal region. During each step, participants are instructed to take 10 slow, deep breaths, directing airflow toward the therapist's hands. |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) |
| 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| Measure | Description | Time Frame |
|---|---|---|
| 1. Forced Vital Capacity (FVC) | 1. Forced Vital Capacity (FVC) Unit of Measure: liters (L) | 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| Forced Expiratory Volume in 1 second (FEV1) | Forced Expiratory Volume in 1 Second (FEV1) Unit of Measure: liters (L) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Siou Pin Huang, PT (Physical Therapist) | Contact | +886 988 366 335 | qaz9650921@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaohsiung Veterans General Hospital | Recruiting | Kaohsiung City | Taiwan |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Jun 9, 2026 | Jun 9, 2026 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D000784 | Aortic Dissection |
| D003324 | Coronary Artery Disease |
| D006349 | Heart Valve Diseases |
| D001014 | Aortic Aneurysm |
| ID | Term |
|---|---|
| D000094665 | Dissection, Blood Vessel |
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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|
| Routine Physical therapy | Behavioral | Participants in the control group will receive routine physical therapy only, including out-of-bed activities, incentive spirometry training (Triflow), and functional exercises. No additional myofascial release therapy will be provided. |
|
| 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| FEV1/FVC ratio | FEV1/FVC Ratio Unit of Measure: percentage (%) | 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| Maximal Voluntary Ventilation (MVV) | Maximal Voluntary Ventilation (MVV) Unit of Measure: liters/minute (L/min) | 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| Middle and Lower chest wall mobility | Chest Wall Mobility Unit of Measure: centimeters (cm) | 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| Diaphragm and sternocleidomastoid surface electromyography (sEMG) | Diaphragm Surface Electromyography Activity Sternocleidomastoid Surface Electromyography Activity Unit of Measure: microvolts (µV) | 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| Pain intensity | Pain intensity measured using the Numeric Rating Scale (NRS). (0-10) | 1. Baseline 2. Day 0-5 post-ICU transfer 3. Week 1 |
| D000094683 |
| Acute Aortic Syndrome |
| D001018 | Aortic Diseases |
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D001161 | Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |