Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study aims to investigate the effect of cardiopulmonary rehabilitation on cardiorespiratory parameters and functional capacity in patients with pulmonary hypertension.
Pulmonary hypertension is a progressive disease associated with reduced exercise capacity, respiratory muscle weakness, and impaired quality of life. Exercise training and respiratory muscle training have been shown to improve physical performance and quality of life in patients with pulmonary hypertension.
forty-two medically stable patients with Group III pulmonary hypertension due to lung diseases (obstructive and restrictive) will participate in this comparative experimental study. Participants will receive cardiopulmonary rehabilitation consisting of moderate-intensity interval aerobic training and inspiratory muscle training in addition to routine medical treatment. Outcome measures will include echocardiographic parameters, pulmonary function, six-minute walk distance, estimated VO2max, dyspnea severity, and quality of life. The study aims to evaluate the influence of cardiopulmonary rehabilitation on cardiorespiratory adaptation in patients with pulmonary hypertension.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group III PH with obstructive lung disease | Experimental | Group (A), (n =16) patients with group III PH with obstructive lung disease will receive cardiopulmonary Rehabilitation in the form of moderate-intensity interval aerobic training and inspiratory muscle training in addition to the routine medical treatment. |
|
| group III PHT with restrictive lung disease | Experimental | group (B), (n =16) patients with group III PHT with restrictive lung disease will receive cardiopulmonary rehabilitation in the form of moderate-intensity interval aerobic training and inspiratory muscle training in addition to the routine medical treatment. |
|
| control group III PH with obstructive lung disease | Experimental | Group (c), (n =5) patients with group III PH with obstructive lung disease will receive medical treatment only |
|
| control group III PHT with restrictive lung disease | Experimental | Group (D), (n =5) patients with group III PH with restrictive lung disease will receive medical treatment only |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cardiopulmonary rehabilitation in the form of moderate-intensity interval aerobic training | Behavioral | Training will be conducted on a treadmill three times weekly for 12 weeks. Exercise intensity will progress from 30-40% to 60-70% of target heart rate. Each session will last 30 minutes and include warm-up and cool-down periods. |
| Measure | Description | Time Frame |
|---|---|---|
| 6-minute walk distance | total distance walked in 6 minutes | 12 weeks |
| Maximal Oxygen Consumption | Estimated VO2max | 12weeks |
| spirometry | FEV1, FVC, FEV1/FVC, MVV | 12weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Dyspnea Severity | Modified Borg Scale | 12weeks |
| change Pulmonary Artery Pressure | pulmonary artery pressure estimated by ECHO | 12weeks |
Not provided
Inclusion Criteria:
- a)Medically stable pulmonary hypertension patients who were under optimized medical therapy. b)Pulmonary artery pressure ≥ 25 mmHg confirmed by RT side heart catheterization.
c)Forty two male patients with group 3 pulmonary hypertension (Chest cause) include Obstructive lung disease ( COPD and sleep apnea ) and restrictive lung disease (ILD). d)The patients' ages will range from 45 to 65 years old. e)BMI (25 - 34.9) kg/m2. f)World Health Organization (WHO) classification of functional classes II to III ( class II are patients with pulmonary hypertension who have a mild limitation of physical activity )(class III are patients with pulmonary hypertension who have a marked limitation of physical activity
Exclusion Criteria:
g)Uncontrolled systemic HTN. h)Other types of pulmonary hypertension.. i)Smoker j)Any condition of kidney failure. k)Neurological or musculoskeletal conditions that interfere with gait
l)Impaired vision and/or hearing.
m)Patients who are unable to follow verbal instructions. n)acute exacerbation condition. o)unstable angina, serious cardiac dysrhythmias on resting ECG.
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rana Essam El Din Abd Elbar, Assistant lecturer | Contact | 01013981766 | rana.essam@acu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| NESREEN GHAREEB MOHAMED EL-NAHAS, Prof PT | faculty of P.T. Cairo University | Study Chair |
| HEBA AHMED ALI ABDEEN, Prof | faculty of P.T. Cairo University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Physical Therapy ,Cairo University | Giza | Egypt |
to protect participant confidentiality
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Inspiratory Muscle Training | Device | inspiratory muscle training will be performed using a Threshold Inspiratory Muscle Trainer (Philips Respironics). Training intensity will correspond to moderate-to-severe effort (3-5 on the Modified Borg Scale). |
|
| Medical treatment | Other | medication |
|
| change of total score of SF-12 Questionnaire) Quality of Life | more increase scores more increase quality of life | 12weeks |
| HEND ABD EL-MONAEM ABD EL-MONAEM, Lecturer of physical therapy |
| faculty of P.T. Cairo University |
| Study Chair |
| REEM IBRAHIM EL KORASHY, prof of pulmonology | Cairo University | Study Chair |