Rhythm Psychophysics With Parkinson's Patients

Rhythm Psychophysics With Parkinson's Patients

The goal of this interventional study is to understand how the rhythmic abilities of individuals in the early stages of Parkinson's Disease (PD) are impacted by their levels of dopamine. The main questions it aims to answer are:

• Does dopamine shelter the ability to generate and maintain a regular tapping rhythm in the presence of disrupting sensory information?
• Does dopamine allow the adaptation of tapping speed in the presence of changing sensory information?
• Is the engagement of the motor system useful to improve the detection of changes in the tempo of sensory information?

Participants will be asked to perform a battery of simple rhythmic tasks On and Off medication to evaluate the effect of dopamine on their rhythmic skills.

Inclusion Criteria:

• Parkinson's Disease diagnostic
• Stage 1 or 2 Hoenh-Yahr scale
• Taking immediate-release Levodopa
• MoCA score of 26 or above

Exclusion Criteria:

• Dementia
• Other neurodegenerative disease
• History of substance abuse
• History of hearing disorders
• History of neuropsychiatric disease