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This prospective observational cohort study was designed to compare the risk of catheter thrombosis and catheter-related infection between adult patients who underwent temporary hemodialysis catheter insertion in the emergency department and those who underwent catheter insertion in the hemodialysis unit.
The study was conducted at Antalya Training and Research Hospital. Adult patients aged 18 years and older who underwent hemodialysis catheter insertion in either the emergency department or the nephrology hemodialysis unit were included. A total of 398 patients were enrolled between December 1, 2024, and December 1, 2025. Demographic and clinical data were collected, and catheter-related complications occurring within 10 days after catheter insertion were assessed using hospital records and follow-up data.
Hemodialysis catheters are frequently used as temporary vascular access in patients requiring urgent or ongoing hemodialysis. Although these catheters provide rapid access for dialysis, catheter-related complications such as thrombosis and infection may result in catheter dysfunction, interruption of dialysis, repeated catheter placement, increased morbidity, and additional healthcare burden.
In emergency departments, temporary hemodialysis catheters are often inserted under urgent clinical conditions. Although standard aseptic and antiseptic measures are applied, factors such as limited preparation time, clinical instability of the patient, and the need for rapid dialysis may affect the risk of catheter-related complications. In contrast, catheter insertion in a hemodialysis unit is generally performed in a more controlled clinical environment.
This prospective observational cohort study compared two groups of adult patients: those who underwent temporary hemodialysis catheter insertion in the emergency department and those who underwent catheter insertion in the nephrology hemodialysis unit. The primary focus was to evaluate whether the catheter insertion setting was associated with differences in the development of catheter thrombosis and catheter-related infection within ten days after catheter placement.
The study included 398 adult patients treated at Antalya Training and Research Hospital between December 1, 2024, and December 1, 2025. Demographic and clinical data were collected, and complications occurring within ten days after catheter insertion were assessed using hospital records and follow-up data. The findings of this study may help determine whether additional preventive measures are needed for hemodialysis catheter insertion procedures performed in emergency department settings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Emergency Department Hemodialysis Catheter Group | Adult patients who underwent temporary hemodialysis catheter insertion in the emergency department. Participants were followed for 10 days after catheter insertion to assess the development of catheter thrombosis and catheter-related infection. | ||
| Hemodialysis Unit Catheter Group | Adult patients who underwent temporary hemodialysis catheter insertion in the nephrology hemodialysis unit. Participants were followed for 10 days after catheter insertion to assess the development of catheter thrombosis and catheter-related infection. |
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of Catheter-Related Infection | The incidence of catheter-related infection will be assessed in adult patients who underwent temporary hemodialysis catheter insertion in either the emergency department or the hemodialysis unit. Catheter-related infection will be recorded based on clinical evaluation, laboratory findings when available, and hospital records during the 10-day follow-up period after catheter insertion. | Within 10 days after hemodialysis catheter insertion |
| Incidence of Catheter Thrombosis | The incidence of catheter thrombosis will be assessed in adult patients who underwent temporary hemodialysis catheter insertion in either the emergency department or the hemodialysis unit. Catheter thrombosis will be recorded based on clinical evaluation and hospital records during the 10-day follow-up period after catheter insertion. | Within 10 days after hemodialysis catheter insertion |
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Inclusion Criteria:
Exclusion Criteria:
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The study population consisted of adult patients aged 18 years and older who underwent temporary hemodialysis catheter insertion in either the emergency department or the nephrology hemodialysis unit at Antalya Training and Research Hospital between December 1, 2024, and December 1, 2025. Participants were followed for 10 days after catheter insertion to evaluate the development of catheter thrombosis and catheter-related infection.
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| Name | Affiliation | Role |
|---|---|---|
| MEHMET AKCIMEN | University of Health Sciences, Antalya Training and Research Hospital | Principal Investigator |
| MURAT DUYAN | University of Health Sciences, Antalya Training and Research Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Health Sciences, Antalya Training and Research Hospital | Antalya | konyaaltı | 07100 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31585477 | Background | Buetti N, Timsit JF. Management and Prevention of Central Venous Catheter-Related Infections in the ICU. Semin Respir Crit Care Med. 2019 Aug;40(4):508-523. doi: 10.1055/s-0039-1693705. Epub 2019 Oct 4. | |
| 9356690 | Background | Leblanc M, Bosc JY, Paganini EP, Canaud B. Central venous dialysis catheter dysfunction. Adv Ren Replace Ther. 1997 Oct;4(4):377-89. doi: 10.1016/s1073-4449(97)70026-8. |
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Individual participant data will not be shared due to privacy and confidentiality restrictions. The data used in this study contain patient-level clinical information, and no specific consent for public or external sharing of individual participant data was obtained. Only aggregated and anonymized results may be reported in scientific publications.
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| ID | Term |
|---|---|
| D055499 | Catheter-Related Infections |
| D058186 | Acute Kidney Injury |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D007239 | Infections |
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
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| 31806658 | Background | Fisher M, Golestaneh L, Allon M, Abreo K, Mokrzycki MH. Prevention of Bloodstream Infections in Patients Undergoing Hemodialysis. Clin J Am Soc Nephrol. 2020 Jan 7;15(1):132-151. doi: 10.2215/CJN.06820619. Epub 2019 Dec 5. |
| D052776 |
| Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |