Intensive Care Outcome Prediction Using Admission Carbohydrate-deficient Transferrin

IMPACT - Intensive Care Outcome Prediction Using Admission Carbohydrate-deficient Transferrin A Prospective Single-center Cohort Study

The goal of this observational study is to learn whether hazardous alcohol consumption, measured objectively by carbohydrate-deficient transferrin (CDT) levels at intensive care unit (ICU) admission, is associated with worse outcomes in critically ill patients. The main question it aims to answer is:

Do elevated CDT levels at ICU admission predict increased short-term mortality and adverse clinical outcomes in adult non-traumatic ICU patients? Participants admitted to the intensive care unit via the emergency department will have CDT levels measured as part of the study. Researchers will then collect and analyze clinical data, including mortality, duration of mechanical ventilation, delirium, ICU length of stay, renal replacement therapy, and ICU readmission rates, during hospitalization and follow-up.

Inclusion Criteria:

• all patients ≥ 18 admitted to the Department of Emergency Medicine and subsequently transferred to an in-house intensive care unit (ICU)

Exclusion Criteria:

• Patients transferred to other hospital departments prior to completion of intensive care
• Patients admitted directly to the ICU without passing the ED
• Patients admitted to intermediate care units
• Patients with pre-existing or newly diagnosed hepatic cirrhosis
• Patients with known or obvious pregnancy will be excluded.
• Patients with no vascular access