Impact of Radiotherapy on Survival in Breast Cancer Patients | NCT07631962

Studies
Impact of Radiotherapy on Survival in Breast Cancer Patients

NCT07631962

Sponsor

Motamed Cancer Institute

Status

Completed

Last Update Posted

Jun 8, 2026Actual

Enrollment

1,030Actual

Phase

Not provided

Conditions

Breast Cancer
Radiotherapy

Interventions

radiotherapy

Countries

Not provided

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Jun 2026

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 1, 1998Actual

Primary Completion Date

Feb 1, 2008Actual

Completion Date

Jan 1, 2025Actual

First Submitted Date

May 28, 2026

First Submission Date that Met QC Criteria

Jun 3, 2026

First Posted Date

Jun 8, 2026Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 3, 2026

Last Update Posted Date

Jun 8, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Yes

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

FDAAA801 Violation

Not provided

Description Module

Brief Summary

In this study, using a large retrospective cohort, the investigators evaluate the impact of RT on disease-free survival and overall survival of patients with BC. The aim is to determine the true role of radiotherapy in improving patient outcomes and to provide a basis for designing more precise treatment strategies in the future.

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

1,030Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Breast Cancer Patients who underwent RT			Radiation: radiotherapy
Breast Cancer Patients who did not underwent RT

Interventions

Name	Type	Description	Arm Group Labels	Other Names
radiotherapy	Radiation	Radiotherapy after BCS surgery in accordance to standard breast cancer guidelines	Breast Cancer Patients who underwent RT

Measure	Description	Time Frame
Survival		25 years

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

-BC patients diagnosed between January 1998 and February 2008 in the Motamed Breast Cancer Research in Tehran, Iran.

Exclusion Criteria:

Male patients.
Patients with missing LPFS and OS information (zero encounter/follow-up).

Accepts Healthy Volunteers

Sex

Female

Sex/Gender Based

Yes

Sex/Gender Description

Females

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

BC patients diagnosed between January 1998 and February 2008 were identified from prospectively maintained breast cancer registries in the Motamed Breast Cancer Research in Tehran, Iran.

Sampling Method

Non-Probability Sample

Condition Browse Module

MeSH Terms

ID	Term
D001943	Breast Neoplasms

Ancestor Terms

ID	Term
D009371	Neoplasms by Site
D009369	Neoplasms
D001941	Breast Diseases
D012871	Skin Diseases

Browse Leaves

Not provided

Browse Branches

Not provided