Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The primary objective of this clinical protocol is to evaluate the physiological responses of dental tissues during active orthodontic treatment. By focusing on standardized force application and precise pulp vitality monitoring, this study aims to ensure both treatment efficacy and patient safety. The clinical intervention is strictly divided into two systematic procedures:Orthodontic Force Application: Orthodontic force is exerted in strict compliance with the established standard treatment protocol. A continuous force of approximately 150g is applied to the target teeth and precisely calibrated using a specialized tension gauge.Pulse Oximetry (SpO2) Measurement: To guarantee optimal data accuracy, the target teeth are completely isolated using cotton rolls to manage moisture. The dental chair light is turned off during the procedure to eliminate any ambient optical interference with the sensor. Measurements are performed three times consecutively, and the arithmetic mean is calculated as the final representative value.In conclusion, this dual-step protocol provides a rigorous and reproducible framework for orthodontic research. The combination of controlled mechanical loading and standardized SpO2 monitoring minimizes external variables, thereby enhancing the reliability of the clinical outcomes.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Orthodontic Force Application | Experimental | An orthodontic force of approximately 150g is applied to the target teeth and verified using a tension gauge. Pulp vitality (SpO2) is measured three times consecutively under moisture isolation (cotton rolls) and with the dental chair light turned off to prevent optical interference. The average SpO2 value is recorded |
|
| Control Group | No Intervention | Subjects in this group do not receive any active orthodontic force application. Baseline pulp vitality (SpO2) measurements are recorded using the exact same clinical protocol (moisture isolation, dental chair light turned off, and 3 consecutive readings to obtain the mean value) for comparative analysis |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Orthodontic Force Application | Device | Application of a controlled mechanical orthodontic force calibrated at approximately 150g using a tension gauge. This intervention is executed during designated clinical visits to initiate tooth movement, while pulp blood flow changes are subsequently monitored. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Dental Pulp Oxygen Saturation (SpO2) Levels | Dental pulp oxygen saturation levels are measured in percentages (%) using a customized pulse oximeter probe adapted for dental use. The objective is to evaluate the physiological microcirculatory response of the canine pulp following orthodontic force application. | Baseline (pre-force), 20 minutes, 24 hours, 7 days, and 4 weeks post-force application |
| Measure | Description | Time Frame |
|---|---|---|
| Alveolar Bone and Root Anatomical Measurements on CBCT | Three-dimensional anatomical variables are measured secondarily from pre-existing Cone-Beam Computed Tomography (CBCT) scans using specialized imaging software. Variables include cortical bone thickness (mm) at the canine apex region, root apex-to-cortical plate distance (mm), and total root length (mm). These baseline metrics will be correlated with the observed SpO2 changes. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Lam Nguyen Le, Assoc. Prof. | Faculty of Odonto-Stomatology, Can Tho University of Medicine and Pharmacy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Can Tho University of Medicine and Pharmacy | Can Tho | 900000 | Vietnam |
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Baseline (at the time of the pre-existing CBCT scan prior to the canine retraction phase) |