Home-Based Tele-Rehabilitation for Respiratory Function in Children With Duchenne Muscular Dystrophy

Feasibility and Preliminary Clinical Effects of a Home-Based, Remotely Delivered Respiratory Rehabilitation Program for Children With Duchenne Muscular Dystrophy

This study evaluates the feasibility and preliminary clinical effects of a home-based tele-rehabilitation program aimed at improving respiratory function in children with Duchenne Muscular Dystrophy (DMD).

This is a prospective single-arm interventional study evaluating a 6-week home-based tele-rehabilitation program for respiratory function in children with Duchenne Muscular Dystrophy. The intervention includes weekly remote education sessions and home-based exercises, with assessments conducted before and after the intervention and a 2-week follow-up for adherence monitoring.

Inclusion Criteria:

• Children aged 3 years or older with genetically confirmed Duchenne muscular dystrophy
• Participants who are able to understand the study procedures and appropriately participate in the study

Exclusion Criteria:

• Requirement for daytime ventilator support or invasive mechanical ventilation via tracheostomy (nighttime non-invasive ventilation such as positive airway pressure ventilation is allowed)
• History of peripheral nerve injury
• History of major surgery within 12 weeks prior to enrollment or expected major surgery during the study period
• History of central nervous system disorders (e.g., cerebral infarction or spinal cord injury)
• Severe cognitive impairment or other conditions that may interfere with participation in the study procedures