This study aimed to evaluate the effects of different capillary blood sampling techniques on blood glucose measurement results in people with diabetes. Blood glucose measurements obtained from the first and second capillary blood drops after antiseptic application were compared. In addition, measurements obtained with and without finger squeezing were evaluated. The findings may contribute to improving standardization in capillary blood glucose monitoring procedures and reducing unnecessary repeated finger punctures in clinical practice.

This methodological and experimental study evaluated whether different capillary blood sampling techniques influence blood glucose measurement results in people with diabetes. The study compared glucose measurements obtained from the first and second capillary blood drops and also evaluated measurements performed with and without finger squeezing under standardized clinical conditions. The findings are expected to contribute to the standardization of capillary blood glucose monitoring procedures and improve clinical practice by reducing unnecessary repeated finger punctures and enhancing participant comfort.

Inclusion Criteria:

• Aged 18 years or older
• Diagnosed with diabetes mellitus
• Provided written and verbal informed consent to participate in the study
• Eligible for blood glucose measurement after at least 6 hours of fasting
• No condition preventing capillary blood sampling from the fingertip
• Physically and mentally able to undergo the measurement procedures specified in the study

Exclusion Criteria:

• Presence of a physical disability or deformity affecting fingertip blood glucose measurement
• Presence of coagulation disorders (e.g., hemophilia) or severe medical conditions affecting blood sampling
• Use of steroids within the previous 24 hours that could affect blood glucose levels
• Presence of physical or mental conditions limiting compliance with study procedures
• Inability or unwillingness to provide informed consent

Adults with diabetes who were hospitalized in the internal medicine clinics of a state hospital during the study period and met the study inclusion criteria.

Individual participant data will not be publicly available due to confidentiality and privacy considerations. However, statistical data may be provided by the corresponding author upon reasonable request.