Variable Intense Training for Ataxia and Locomotion

Feasibility and Potential Efficacy of High-intensity Gait Training in Individuals With Cerebellar Damage

The goal of this study is to evaluate the feasibility and potential preliminary efficiency of high-intensity training focused on stepping in variable contexts as compared to conventional training in individuals with cerebellar disease

The goal of this study is to evaluate the feasibility and potential preliminary efficiency of high-intensity training focused on stepping in variable contexts as compared to conventional training in individuals with cerebellar disease

Inclusion Criteria:

• Ages 18-85
• >6 months following brain injury or diagnosis of cerebellar dysfunction
• A total score of > 4 on items 5-8 on the SARA for the ipsilateral limb
• Ability to ambulate 10 m at self-selected gait speeds (SSV) <1.2 m/s with no greater than minimal physical assistance permitted for postural stability only, but with below knee bracing and/or assistive device as needed
• Weight < 350 pounds
• Able to follow 1-step command
• Medical clearance to participate

Exclusion Criteria:

• Uncontrolled cardiopulmonary or metabolic disease that limits exercise participation, active heterotopic ossification, recurrent history of lower extremity fractures, previous orthopedic or other peripheral or central neurologic injury that may impair locomotor activities
• Currently participating in other physical therapy
• >50 units of Botox within the past three months in the lower extremity OR in the lower extremity, but above the knee if the participant wears an ankle-foot-orthosis
• Individuals deemed not stable between Pre-Baseline Testing and Baseline Testing