Prospectively study the correlation between Leucine-rich α2-glycoprotein (LRG) and clinical/endoscopic/histological disease activity in patients with inflammatory bowel disease (IBD) in Europe.

Inclusion Criteria:

1. ≥18 years
2. Patient with confirmed diagnosis of IBD
3. Patient with planned endoscopy (ileocolonoscopy for Crohn's disease (CD)/ulcerative colitis (UC) or sigmoidoscopy for UC) for the assessment of endoscopic disease activity according to routine practice
4. willing to provide informed consent

Exclusion Criteria:

1. Patient with IBD unspecified
2. Patient with ileo- or colostomy
3. Patient with total colectomy
4. Women that are pregnant

patients with IBD