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This study evaluated the association between baseline frailty (mFI-11) and acute illness severity (SAPS 3) with real hospital costs in adult patients admitted to the Intensive Care Unit (ICU). The objective was to determine if frailty and severity are independent predictors of resource consumption.
A retrospective cohort study was conducted at Hospital H+ Querétaro involving 142 adult patients admitted to the ICU between January 2024 and May 2025. Baseline frailty was calculated using the 11-item Modified Frailty Index (mFI-11), and acute severity was assessed with the SAPS 3 score. Total hospital costs were obtained from institutional financial records. Multivariate models were used to adjust for comorbidities (Charlson Index) and other clinical variables to identify independent determinants of hospital expenditure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICU Patient Cohort | All adult patients (≥18 years) admitted to the ICU during the study period with complete medical and financial records. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Total Real Hospital Cost. | Other | The total monetary expenditure (expressed in Mexican Pesos) generated during the hospital stay, as recorded in the institutional financial database. |
| Measure | Description | Time Frame |
|---|---|---|
| Total Real Hospital Cost | The total monetary expenditure (in local currency) recorded in the institutional administrative database for the hospital episode, from admission to discharge or death. | From ICU admission to hospital discharge (approximately 17 months of data collection period). |
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Inclusion Criteria:
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Pacientes adultos (≥18 años) admitidos a la Unidad de Cuidados Intensivos del Hospital H+ Querétaro entre el 1 de enero de 2024 y el 31 de mayo de 2025. Se incluirán únicamente aquellos con expedientes clínicos completos que permitan el cálculo del índice de fragilidad modificado de 11 ítems (mFI-11), el puntaje de severidad SAPS 3 y el índice de comorbilidad de Charlson, así como disponibilidad de registros institucionales de costos hospitalarios reales. Se excluirán pacientes con información incompleta en variables principales, transferidos de otras instituciones sin datos basales suficientes, con inconsistencias significativas en los registros de costos, o reingresos en los que no sea posible atribuir de manera independiente los costos al episodio índice.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital H+ Querétaro, Santiago de Querétaro, Querétaro | Querétaro City | Querétaro | 7600 | Mexico |
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| ID | Term |
|---|---|
| D000073496 | Frailty |
| D016638 | Critical Illness |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |
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