Laparoscopic-endoscopic Surgery Assisted Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer

A Prospective Registry Study of Laparoscopic-endoscopic Cooperative Surgery Assisted Sentinel Lymph Node Navigation Surgery for Early Gastric Cancer

This study is to evaluate the safety and efficacy of dual-endoscope assisted sentinel lymph node navigation surgery for early gastric cancer (EGC).

Inclusion Criteria:

• Preoperative assessment indicating that the tumor was confined to the mucosa or submucosa, consistent with the diagnosis of early gastric cancer.
• Patients who required additional surgical intervention following initial endoscopic submucosal dissection (ESD) based on postoperative pathological evaluation.
• Patients and their families fully understood the procedure, requested dual-endoscope assisted sentinel lymph node navigation surgery, agreed to participate in this clinical study, and signed the informed consent form.

Exclusion Criteria:

• Preoperative assessment indicating suspected lymph node or distant metastasis.
• History of complex abdominal surgery rendering laparoscopic treatment infeasible.
• Participation in another clinical trial within 4 weeks prior to enrollment or currently participating in another trial.
• History of severe psychiatric disorders.
• Pregnant or lactating women.
• Uncontrolled infection prior to surgery.
• Presence of other malignancies or comorbidities that may significantly affect survival.
• Any other conditions deemed by the investigators as unsuitable for participation, or refusal by the patient or family to enroll.
• Cardiopulmonary, hepatic, and renal functions were unsufficient to tolerate the surgery.