Objective: This study aims to determine the effect of web-based cancer awareness education in schools on students' knowledge levels, help-seeking attitudes, and stigma attitudes.

Method: The Web-Based Adolescent Cancer Education (WAKE) study was planned as a school-based, randomized controlled experimental study. Qualified high schools in the public sector of Izmir province will constitute the study population. Private schools are excluded for adolescents whose additional needs cannot be met in inclusive education. Two schools will be selected using a purposive sampling method (15-18 age group) and assigned to the experimental and control groups. This will prevent interaction between students in both schools. Students in each school will be listed, and assignments to groups will be made using a web-based randomizer application with randomly selected numbers (https://www.randomizer.org/). Data will be collected using the Cancer Awareness Scale (CAM), the Cancer Stigma Scale (CASS-T), and a Basic Demographic Questionnaire. In the evaluation of the data, descriptive statistics (number, percentage, and statistic) will be used, and repeated measures analysis of variance will be employed to assess the effect of the intervention. Differences in results between the experimental and control groups will be tested using multiple regression methods.

Inclusion Criteria:

• Being a student aged 15-18 in selected schools
• Volunteers who have withdrawn must agree to participate
• Parents must fill out an informed consent form
• Lack of literacy skills

Exclusion Criteria:

• Having a problem that will prevent communication
• Students who do not agree to the study
• Students whose parents' permission cannot be obtained
• Not being able to access and use the internet
• The student wants to voluntarily withdraw from the research