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| Name | Class |
|---|---|
| Kingston University | OTHER |
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The goal of this clinical trial (randomised, double-blind, placebo-controlled crossover study) is to investigate whether supplementation with Ecklonia cava, a natural extract derived from brown seaweed, affects exercise performance and physiological responses in trained cyclists.
The main questions it aims to answer are:
Does Ecklonia cava supplementation improve cycling performance, including power output during steady-state exercise and short maximal sprints? Does Ecklonia cava supplementation influence physiological responses to exercise, such as blood glucose, blood lactate, heart rate, and oxygen consumption?
Researchers will compare Ecklonia cava supplementation to a placebo (a look-alike substance with no active ingredients) to determine whether the supplement has any effect on performance or physiological responses.
In this crossover design, all participants will receive both the Ecklonia cava supplement and the placebo on separate occasions, with a washout period between conditions.
Participants will:
Ingest either Ecklonia cava or a placebo 30 minutes before exercise testing Complete a 60-minute cycling protocol at a moderate intensity Perform repeated short-duration maximal sprint efforts following the steady-state exercise Attend laboratory testing sessions under both supplement and placebo conditions Undergo measurements of physiological responses, including blood glucose, blood lactate, heart rate, oxygen consumption, and respiratory exchange ratio Have exercise performance assessed through measures of power output during cycling
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo Supplementation | Placebo Comparator |
| |
| Ecklonia Cava Supplementation | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo | Dietary Supplement | Placebo Supplementation |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Peak Power Output During Sprint Performance (Watts) | Peak power output achieved during 20-second maximal sprint efforts performed following a fixed-intensity (55% Wmax) 60-minute cycling protocol | Immediately after the 60-minute submaximal cycling protocol, 30 minutes after supplementation |
| Mean Power Output During Sprint Performance (Watts) | Mean power output recorded during repeated 20-second maximal sprint efforts following steady-state cycling | Immediately after the 60-minute submaximal cycling protocol, 30 minutes after supplementation |
| Blood Lactate Concentration During Sprint Cycling (mmol/L) | Blood lactate concentration measured following each repeated sprint efforts (3) | Repeated sprint cycling (3) completed immediately after the 60-minute submaximal cycling protocol, a blood sample taken 2 minutes after each sprint cycling bout. Following each 30-minute supplementation protocol. |
| Blood Glucose Concentration During Sprint Cycling (mmol/L) | Blood glucose concentration measured following repeated sprint efforts | Repeated sprint cycling (3) completed immediately after the 60-minute submaximal cycling protocol, a blood sample taken 2 minutes after each sprint cycling bout. Following each 30-minute supplementation protocol. |
| Measure | Description | Time Frame |
|---|---|---|
| Heart Rate During Submaximal Cycling (beats per minute) | Average heart rate measured during a 60-minute steady-state cycling protocol performed at 55% maximal power output | During the 60-minute submaximal cycling protocol, 30 minutes after supplementation (each condition) |
| Blood Lactate Concentration During Submaximal Cycling (mmol/L) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Applied and Human Sciences | Kingston upon Thames | KT1 2EE | United Kingdom |
Available on request.
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| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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| Supplement |
| Dietary Supplement |
Ecklonia Cava Supplementation |
|
Blood lactate concentration measured during steady-state cycling at 55% maximal power output |
| Every 20-minutes during the 60-minute submaximal cycling protocol, 30 minutes after supplementation |
| Blood Glucose Concentration During Submaximal Cycling (mmol/L) | Blood glucose concentration measured during steady-state cycling at 55% maximal power output | Every 20-minutes during the 60-minute submaximal cycling protocol, 30 minutes after supplementation |
| Oxygen Consumption (VO₂) During Submaximal Cycling (ml/kg/min) | Oxygen consumption measured using indirect calorimetry during steady-state cycling | During the 60-minute submaximal cycling protocol, 30 minutes after supplementation |
| Respiratory Exchange Ratio (RER) During Submaximal Cycling | Respiratory exchange ratio measured during steady-state cycling using expired gas analysis | During the 60-minute submaximal cycling protocol, 30 minutes after supplementation |