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This study aims to investigate the effects of smoking on pain threshold, cervical position sense, and grip strength in women. Measurements will include pressure pain threshold (PPT), cervical position sense (CPS), grip strength, and pinch strength.
Smoking is widely recognized as one of the leading preventable causes of mortality and morbidity worldwide and constitutes a major public health problem. Smoking is thought to negatively influence pain perception, proprioceptive sensory feedback, and muscle performance. In this context, examining the combined effects of smoking on pain threshold, CPS, and grip strength in women may contribute to a more comprehensive understanding of the multidimensional impact of smoking on the neuromuscular and sensory systems. Therefore, the aim of this study is to investigate the effects of smoking on pain threshold, CPS, and grip strength in women.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| observational study | Other | observational case control study |
| Measure | Description | Time Frame |
|---|---|---|
| Grip strenght | Participants will be instructed to grasp the device tip between the thumb and the lateral aspect of the index finger's middle phalanx and to apply maximal force for 3 seconds, followed by relaxation. | The measurements will be lasted 5-10 minutes. |
| Pain pressure threshold | Measurements will obtained from anatomical landmarks that have been frequently used in previous studies and reported to be reliable and sensitive. | The measurements will last 5-10 minutes. |
| Cervical Position Sense | Using the CROM device, deviations from neutral head position were recorded in all three anatomical planes. With eyes closed, participants were then asked to perceive a target position passively guided by the examiner. | The measurements will take 5-10 minutes. |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy women aged 18-45, both smokers and non-smokers
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Karabuk University | Karabük | Karabük Province | 78050 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Audette, I., Dumas, J. P., Côté, J. N., & De Serres, S. J. (2010). Validity and between-day reliability of the cervical range of motion (CROM) device. Journal of Orthopaedic & Sports Physical Therapy, 40(5), 318-323. Bartley, E. J., & Fillingim, R. B. (2013). Sex differences in pain: a brief review of clinical and experimental findings. British journal of anaesthesia, 111(1), 52-58. Bhattacharyya, A., Hopkinson, L. D., Nolet, P. S., & Srbely, J. (2023). The reliability of pressure pain threshold in individuals with low back or neck pain: a systematic review. British Journal of Pain, 17(6), 579-591. Benowitz, N. L., Lessov-Schlaggar, C. N., Swan, G. E., & Jacob III, P. (2006). Female sex and oral contraceptive use accelerate nicotine metabolism. Clinical pharmacology & therapeutics, 79(5), 480-488. Binderup, A. T., Arendt-Nielsen, L., & Madeleine, P. (2010). Cluster analysis of pressure pain threshold maps from the trapezius muscle. Computer Methods in Biomechanics and Biomedical Engineering, 13(6), 677-683. Bobos, P., Nazari, G., Lu, Z., & MacDermid, J. C. (2020). Measurement properties of the hand grip strength assessment: a systematic review with meta-analysis. Archives of physical medicine and rehabilitation, 101(3), 553-565. Carrasco-Rios M, Ortolá R, Rodríguez-Artalejo F, García-Esquinas E. Exposure to secondhand tobacco smoke is associated with reduced muscle strength in US adults. Aging (Albany NY). 2019 Dec 9;11(24):12674-12684. doi: 10.18632/aging.102594. Epub 2019 Dec 9. PMID: 31815682; PMCID: PMC6949081. Castien, R. F., van der Wouden, J. C., & De Hertogh, W. (2018). Pressure pain thresholds over the cranio-cervical region in headache: a systematic review and meta-analysis. The journal of headache and pain, 19(1), 9. |
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Data will be kept confidential and will not be shared with third parties.
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| ID | Term |
|---|---|
| D000073865 | Cigarette Smoking |
| D010146 | Pain |
| ID | Term |
|---|---|
| D000073869 | Tobacco Smoking |
| D012907 | Smoking |
| D001519 | Behavior |
| D064424 | Tobacco Use |
| D009461 |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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| Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |