The Value of Time-Dependent Diffusion MRI and Magnetic Resonance Elastography in the Precise Diagnosis and Efficacy Assessment of Breast Cancer

The Value of Time-Dependent Diffusion MRI and Magnetic Resonance Elastography in the Precise Diagnosis and Efficacy Assessment of Breast Cancer

We consecutively enrolled patients presenting with breast space-occupying lesions at our hospital. Medical imaging data from simultaneously acquired ultrafast DCE-MRI, time-dependent diffusion MRI (TDD-MRI), magnetic resonance elastography (MRE), andvirtual magnetic resonance elastography(vMRE), along with clinical and pathological data, were collected. The study aims to evaluate and explore the clinical application value of these multimodal imaging techniques in the precision diagnosis, treatment, and prognosis of breast cancer. The findings are intended to provide a robust imaging basis for formulating and adjusting more precise, individualized treatment plans and prognostic assessments for patients. Ultimately, this research seeks to improve patient quality of life, optimize the allocation of medical resources, and advance the development of precision medicine.

Inclusion Criteria:

1. Age ≥ 18 years old
2. Female patients with BI-RADS class 4 or above breast lesions detected by mammography or ultrasound
3. Perform breast new technology MRI examination (ultra fast DCE-MRI、OGSE 、MRE、vMRE)within one week before biopsy or surgery

Exclusion Criteria:

1. Previously received breast radiotherapy, chemotherapy, surgery, or targeted therapy
2. Unable to cooperate in completing MRI examination
3. The image data contains serious artifacts (such as motion artifacts and metal artifacts), making it impossible to measure parameters
4. The lesion cannot be clearly identified and outlined on the image
5. Pregnant and lactating women
6. Combined with severe liver, liver, and kidney diseases, coagulation dysfunction, or other malignant tumors