Feasibility Study of a Remote Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension

Nonrandomized, Unmasked Feasibility Study of a Remote-based Behavioral Dietary Intervention in Patients With Early to Intermediate AMD: Glucose Lowering for Vision Extension (GLOVE)

The primary goal of the study is to test dietary intervention at glycemic control and carotenoid levels in participants with intermediate age-related macular degeneration.

Inclusion Criteria:

• Diagnosis of early to intermediate AMD with no history of retinal geographic atrophy (cRORA) or exudative disease
• Eating a diet less healthy than average (Healthy Eating Index [HEI] score <61) based on 3 24-hour dietary recalls
• Access to a computer or smart phone for use in the behavioral meetings (we will provide loaners for those lacking a smart phone
• Because the initial questionnaires (ASA24), surveys and informed consent will be on line and in English, only individuals with fluency in English will be included. (They do not need to list English as their primary language.)

Exclusion Criteria:

• HbA1c greater than 6.5%,
• Diabetes or medications used to treat diabetes or obesity (including GLP1 agonists, metformin, glyburide
• Use of statins, niacin or other lipid/cholesterol modifying medications
• Recent cancer (within past 3 years)
• Other retinal or ocular pathology (other than pseudophakia and/or refractive error (between -8 to +8 diopter spherical equivalence)