Identifying Essential Elements of SAP Supports

Identifying the Essential Elements of Case Managers and Peer Support Groups for Prophylaxis Adherence in Rheumatic Heart Disease

CAMPS Plus is a non-randomized extension cohort to assess the non-inferiority of a case manager only (CM) intervention when compared to case manager plus peer support group (CM+PG) to support secondary antibiotic prophylaxis (SAP) adherence in children with RHD

The objective of CAMPS Plus is to determine the minimum intervention needed to achieve secondary antibiotic prophylaxis (SAP) adherence for children newly diagnosed with rheumatic heart disease to further increase affordability and feasibility at scale.

Aim 1: Determine the difference in 1-year SAP adherence rates of children newly diagnosed with RHD in Uganda receiving one of two support strategies: case manager only (CM) and case manager plus peer support group (CM + PG).

Aim 2: Explore implementation determinants among case managers, participants, and participant families to inform deployment of program at scale.

Inclusion Criteria:

1. Between the ages of 5-20 years
2. Have a diagnosis of RHD detected through school-based screening echocardiography

Exclusion Criteria:

1. Medical contraindication to SAP (e.g., bleeding risk, allergy)
2. Co-morbid conditions that have already resulted in prescription of SAP (e.g., HIV, sickle cell disease, renal disease)