Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ.

Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ.

Evaluation of the effect of liquorice nanogel versus diode laser on periodontitis stage Ⅲ clinically and microbiologically by molecular analysis of porphyromonas gingivalis using real time PCR.

Quantitative analysis technique using real time pcr (polymerase chain reaction) was done to detect presence of porphyromonas gingivalis. Pocket depth (PD), Plaque index (PI), gingival index (GI) and Clinical attachment level (CAL) were measured before work and after 3 months postoperatively.

Analysis was made from gingival crevicular fluid samples of the patients using gutta percha paper points.

Inclusion Criteria:

1. Patient had Periodontitis stage III with pocket depth ≥ 6mm; indicated for periodontal surgery or CAL ≥ 5mm.
2. Patient agreed to the surgical procedure and clinical trial.
3. Age ranged between 18-50 years old.

Exclusion Criteria:

• 1: No previous drug was taken affecting bone metabolism. 2- Smoking. 3- Pregnant women and women with menopause. 4- Patients with psychological problems . 5- Patients with abnormal habits. 6- Patients with medical conditions as Diabetes or Hypertension.