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| Name | Class |
|---|---|
| INSERM 1028 | UNKNOWN |
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This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders. Social cognition refers to the ability to understand what others think, feel, or intend, and plays a key role in social relationships and daily interactions.
Main questions this study aims to answer:
This study is a randomized, controlled, monocentric trial evaluating a novel sensory-motor rehabilitation approach for social cognition. The study is based on the hypothesis that perception is interpretative and viewpoint-dependent, and that realizing this through concrete experience could generalize to higher-level cognitive processes required for social understanding.
Participants will attend three visits and complete questionnaires and tasks that assess social understanding before and after the activity, and again one month later.
Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time. Participants will be randomized in one condition.
This research does not involve medication. It consists of simple tasks such as observing and describing visual stimuli, followed by a facilitated discussion.
Neuropsychological tests and questionnaires will be used to measure changes over time.
Expected impact: By inducing concrete perspective-shifts, the intervention aims to improve mentalizing, reduce egocentric biases, and strengthen interpretation of social cues. This bottom-up sensory-motor approach may overcome limitations of classical cognitive remediation programs by promoting deep experiential learning rather than top-down instruction.
If effective, the method may support long-term social reintegration, psychosocial functioning, and inspire wider clinical applications due to its low cost, ease of deployment, and strong ecological engagement.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Immediate intervention | Experimental | Participants receive the visual-perception session shortly after baseline assessment. They complete neurocognitive and social cognition tests before exposure, immediately after, and again at one-month follow-up. |
|
| Delayed Intervention (Wait-list Control) | Active Comparator | Participants complete the same assessments as Arm 1 but receive the intervention only after a waiting period. This arm allows comparison between natural progression and workshop effects prior to exposure. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Visual-illusion social cognition session (immediate) | Behavioral | A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases:
The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues. |
| Measure | Description | Time Frame |
|---|---|---|
| "Faux Pas" test total score |
| Change from pre to post intervention (up to 3 hours) |
| Measure | Description | Time Frame |
|---|---|---|
| Hinting Task |
| Change from pre to post intervention (up to 3 hours) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Joy El KHOURY | Contact | +330437915534 | joy.el-khoury@inserm.fr | |
| Méline Devaluez, PhD | Contact | meline.devaluez@ch-le-vinatier.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CH Le Vinatier | Bron | 69678 | France |
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Anonymized IPD that underlie results in a publication may be shared upon reasonable scientific request following publication of study results.
IPD available after publication of primary results
Requests must be made by qualified researchers for scientific purposes. Data will be shared under controlled access agreement ensuring privacy and ethical standards.
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| ID | Term |
|---|---|
| D012559 | Schizophrenia |
| D011618 | Psychotic Disorders |
| D007088 | Illusions |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
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Two groups will take part: one completing the workshop shortly after inclusion, and one completing it after a delay, allowing comparison over time.
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| Visual-illusion social cognition session (delayed) | Behavioral | A guided session of approximately 45 minutes. The core rehabilitation tool consists of multiple-perspective illusion boxes. Each participant stands on one side of the box and perceives a different shape than their partner. The session unfolds in 3 structured phases: 1. For each illusion : Participants observe objects silently and draw what they see. 2. Perspective confrontation + Card selection: Drawings and interpretation cards are exchanged and discussed. 3. Perspective switching : Participants swap positions to reveal the alternative visual interpretation. The session is followed by a short structured discussion with a psychologist focused on perspective-taking and interpretation of social cues. Delivered after a delay following baseline assessment. |
|
| MASC performance | Number of correct responses Score range 0 - 45 Minimum (0) : No correct mental state inference Maximum (45) : All mental states correctly inferred | Change from pre intervention to follow-up session (up to a month and a half) |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |