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The goal of this observational study is to evaluate the clinical utility of cardiac magnetic resonance (CMR) in patients with acute myocardial infarction (AMI). This is a retrospective and prospective cohort study that has already enrolled a number of patients and will continue to enroll additional patients on a rolling basis.
The main question it aims to answer is:
How does CMR, performed acute phase, contribute to risk stratification, prognostic assessment, and long-term clinical management in patients with AMI?
Participants who have had an AMI will undergo CMR within one week of symptom onset. After discharge, they will be regularly followed up at 1, 3, 6, 9, and 12 months, and then every 6 months thereafter. Clinical outcomes will be collected during each follow-up visit.
This is an ambispective observational cohort study. The study will include patients who have already undergone CMR examination and meet the eligibility criteria, as well as consecutively enrolled patients who will undergo CMR during the prospective study period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AMI |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiac magnetic resonance imaging | Other | Cardiovascular magnetic resonance imaging will be used to assess cardiac structure, function, myocardial injury, infarct size, late gadolinium enhancement, microvascular obstruction, and other CMR-derived parameters. This is an observational cohort study, and no diagnostic test or treatment will be assigned by the investigators. CMR examinations have been or will be performed as part of routine clinical evaluation according to clinical indications. |
| Measure | Description | Time Frame |
|---|---|---|
| Major Adverse Cardiovascular Events (MACE) | A composite of cardiovascular death, non-fatal myocardial infarction, unplanned coronary revascularization, and hospitalization for heart failure. Assessed from the date of index hospitalization through the end of follow-up. | through study completion, an average of 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac Magnetic Resonance (CMR) Imaging Parameters | Presence of microvascular obstruction assessed by late gadolinium enhancement cardiovascular magnetic resonance imaging. | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Patients diagnosed with AMI and who underwent CMR within the acute phase of symptom onset.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Affiliated Hospital of Xuzhou Medical University | Xuzhou | Jiangsu | 221000 | China |
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