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Stroke is a leading cause of long-term disability in adults. Although many individuals regain independent walking ability following stroke, nearly 50% experience persistent gait impairments characterized by asymmetrical walking patterns, slower walking speed, impaired balance, and increased fall risk. These persistent mobility limitations highlight the continued need for innovative rehabilitation strategies that improve gait function during stroke recovery. Split-belt treadmill walking (SBTW), in which each leg walks at a different belt speed, has demonstrated potential to improve step length symmetry in individuals with chronic stroke. However, the effects of SBTW during the subacute stage of stroke recovery, within the first 9 months post-stroke when neuroplasticity may be heightened, remain largely unknown. In addition, previous SBTW studies have not integrated active physiotherapist-led gait retraining into the intervention, despite physiotherapist-led gait rehabilitation representing standard clinical care following stroke. The purpose of this randomized controlled trial is to compare physiotherapist-led gait retraining using a traditional treadmill training protocol to physiotherapist-led gait retraining integrated with a split-belt treadmill training protocol during the first 9 months post-stroke. The study aims to examine the effectiveness of the use of split-belt treadmill training to augment physiotherapist-led gait retraining to improve between-leg gait symmetry and overground walking speed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Split-belt treadmill training | Experimental | Participants will complete 12 gait training sessions over 4 weeks (3 sessions/week) on an instrumented split-belt treadmill involving both split-belt and tied-belt walking conditions. A physiotherapist will provide gait retraining during each training session. |
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| Traditional treadmill training | No Intervention | Participants will complete 12 gait training sessions over 4 weeks (3 sessions/week) on an instrumented treadmill under tied-belt walking conditions only. A physiotherapist will provide gait retraining during each training session. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Split-belt walking training | Behavioral | Participants randomized to the split-belt training group will complete 12 sessions of split-belt treadmill walking training over 4 weeks, delivered 3 times per week. Training will be performed on an instrumented split-belt treadmill and will include split-belt and tied-belt walking conditions. A physiotherapist will provide gait retraining during each session. |
| Measure | Description | Time Frame |
|---|---|---|
| Step length symmetry | Baseline, immediately post-intervention, and at 1-month follow-up | |
| Self-selected gait speeds | Self-selected gait speeds at both comfortable and fast speed will be measured by overground 10 meter walk tests | Baseline, immediately post-intervention, and at 1-month follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Courtney Pollock, PT PhD | Contact | 604-714-4117 | courtney.pollock@ubc.ca | |
| Beier Lin | Contact | beierlin@student.ubc.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| GF Strong Rehabilitation Centre | Vancouver | British Columbia | V5Z 2G9 | Canada |
IPD that underlie results in a publication will be shared.
Beginning 3 months and ending 3 years after the publication of results
The PI will accept a proposal that describes planned analyses and assess the need for a data sharing agreement.
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |