Body Composition, Functional Capacity, and Respiratory Muscle Endurance in Obesity With Restrictive Ventilatory Pattern

Investigation of the Relationship Between Body Composition, Functional Capacity, and Respiratory Muscle Endurance in Individuals With Obesity and a Restrictive Ventilatory Pattern

This observational cross-sectional study aims to examine the relationship between body composition, functional capacity, and respiratory muscle endurance in individuals with obesity and a restrictive ventilatory pattern. A total of 100 adults aged 25-60 years with a body mass index (BMI) ≥30 kg/m² and restrictive pulmonary function findings will be enrolled. Participants will evaluate body composition assessment using bioelectrical impedance analysis, pulmonary function testing by spirometry, respiratory muscle strength and endurance measurements, and functional capacity evaluation using the Six-Minute Walk Test (6MWT). The aim of this study is to evaluate the relationships between stem cell count (SCC), a novel anthropometric indicator called WWI, trunk muscle mass, and functional capacity in obese individuals with a restrictive ventilatory pattern.

Inclusion Criteria:

• Individuals aged between 25 and 60 years
• Individuals with a body mass index (BMI) ≥ 30 kg/m² according to the World Health Organization (WHO) classification
• Individuals demonstrating a restrictive ventilatory pattern (FVC < 80% predicted)
• Individuals who voluntarily agree to participate in the study

Exclusion Criteria:

• Individuals with a Charlson Comorbidity Index (CCI) score of 3 or higher
• Individuals with uncontrolled arrhythmia, hypertension, heart failure, diabetes mellitus, or unstable angina pectoris
• Individuals with cooperation impairments, orthopedic, or neurological conditions that may interfere with assessment or treatment
• Individuals with a history of lower extremity injury or surgery within the last six months
• Individuals diagnosed with diabetes mellitus who have complications such as nephropathy, retinopathy, or neuropathy
• Individuals with concomitant chronic respiratory disease
• Individuals with acute infection
• Individuals with middle ear pathologies (e.g., tympanic membrane rupture or otitis)
• Individuals with a history of spontaneous or trauma-related pneumothorax
• Current smokers
• Pregnant individuals
• Individuals with a STOP-Bang score of 3 or higher
• Individuals currently participating in a structured weight-loss diet program or receiving medical treatment for weight loss during the assessment period
• Individuals who have undergone endoscopic intervention and/or bariatric surgery within the last year