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The aim of this study is to investigate if personalized dosing of antidepressant medications using information gathered at the Personalized Medicine Clinic can improve patients' mental health. The main question it aims to answer is if the Personalized Medicine Clinic can improve depressive symptoms based on the CES-D survey score.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Personalized Medicine Cohort | Patients referred to the Personalized Medicine Clinic for guidance on antidepressant therapy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Personalized Medicine Clinic | Other | Personalized Medicine Clinic services with specific focus on pharmacogenetic recommendations and patient education. |
|
| Measure | Description | Time Frame |
|---|---|---|
| CES-D Survey Score | CES-D survey score is a 20-item self-reported questionnaire that was designed to assess depressive symptoms. The score is from 0-60 with higher numbers indicating greater depressive symptoms. | From enrollment to 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients referred to the Personalized Medicine clinic for genotype-guided drug dosing and selection related to mental health pharmacotherapy as part of clinical care.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Richard B Kim, MD | Contact | 519-685-8500 | 33553 | richard.kim@lhsc.on.ca |
| Denise Keller, PharmD | Contact | 519-685-8500 | 34395 | denise.keller@lhsc.on.ca |
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| ID | Term |
|---|---|
| D000092862 | Psychological Well-Being |
| D003866 | Depressive Disorder |
| ID | Term |
|---|---|
| D010549 | Personal Satisfaction |
| D001519 | Behavior |
| D019964 | Mood Disorders |
| D001523 | Mental Disorders |
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