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| ID | Type | Description | Link |
|---|---|---|---|
| 1R15HD114052 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | NIH |
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The following experiment will be conducted with 15 chronic stroke survivors and 15 control subjects. Subjects will perform hand movements in the virtual reality environment using a head-mounted display. Quest's onboard cameras allow real-time tracking of hand motion, estimating joint angles of the finger and the thumb. For each feedback manipulation condition (i.e., movement amplification or reduction), the estimated joint angles will be multiplied by a factor greater than 1 (amplification) or a factor smaller than 1 (reduction). Then the newly-estimated hand posture will be displayed in the VR environment. Subjects will be randomly assigned into two groups (A and B), who will receive the assistance in a different order. Subjects will perform finger extension under three conditions: no sensory modulation, movement visual feedback (VF) amplification, and movement VF reduction (error augmentation), while their movement muscle activation patterns are recorded.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Visual ROM augmentation followed by visual ROM reduction | Experimental |
| |
| Visual ROM reduction followed by visual ROM augmentation | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Visual ROM augmentation | Device | Finger joint ROM is amplified. |
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| Measure | Description | Time Frame |
|---|---|---|
| Joint range of motion (ROM) | range of motion of individual finger joints under each condition, measured by embedded cameras that digitize individual finger segments | Periprocedural |
| Measure | Description | Time Frame |
|---|---|---|
| Muscle activation | Activation level of hand muscles will be measured using surface EMG electrodes attached to the major hand muscles including extensor digitorum communis, flexor digitorum superficialis, and first dorsal interosseous. | Periprocedural |
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Inclusion Criteria for stroke group:
Exclusion Criteria for both groups:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sang Wook Lee, PhD | Contact | 202-319-6218 | leesw@cua.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Catholic University of America | Recruiting | Washington D.C. | District of Columbia | 20064 | United States |
The investigators do not plan to share IPD but the de-identified data will be shared.
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Visual ROM reduction | Device | Visual feedback of finger joint ROM is reduced. |
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| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |