Digital Patient-Reported Assessment in Older Adults With Acute Leukemia

Feasibility of a Structured Digital Patient-Reported Assessment Pathway in Older Adults With Acute Leukemia: A Prospective Single-Center Pilot Study

This pilot study will evaluate the feasibility of implementing a structured digital patient-reported assessment pathway in adults aged 65 years or older with acute leukemia. Following activation of the institutional MiAsturSalud/SESPA platform, participants will complete the EORTC QLQ-C30 and FACT-Leu remotely after the baseline visit and will repeat the digital assessment at 3-6 months. The primary outcome will be completion of at least 80% of the baseline digital assessment within 7 days. Secondary outcomes will be caregiver assistance requirement, non-completion of the planned digital follow-up assessment, and elapsed completion time. The study is not designed to establish clinical efficacy.

Inclusion Criteria:

• Age 65 years or older.
• Confirmed diagnosis of acute leukemia of myeloid or lymphoid origin.
• Active ambulatory follow-up in the Hematology Service at Hospital Universitario Central de Asturias.
• Ability to understand the questionnaires and provide their own responses, independently or with practical assistance from a caregiver.
• Access to a compatible internet-enabled digital device, either personally or through a caregiver.
• Provision of written informed consent.

Exclusion Criteria:

• Cognitive impairment that, in the treating hematologist's clinical judgment, prevents the participant from understanding the questionnaires or providing their own responses, despite permitted practical assistance from a caregiver.
• Clinical condition that, in the treating hematologist's judgment, precludes completion of the study procedures.
• Persistent inability to access or use the MiAsturSalud/SESPA platform despite reasonable technical support.