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The aim of this clinical trial is to evaluate the effect of detrusor underactivity on the functional and symptomatic outcomes following transurethral resection of the prostate (TURP) in benign prostatic hyperplasia patients presenting with chronic urinary retention.
The main questions it aims to answer are:
Will they restore spontaneous voiding?
They will be divided into 2 comparative groups (each group 45 patients) based on detrusor contractility.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| consists of patients with underactive detrusor (bladder contractility index less than 100). | Active Comparator | • Group (B) - Underactive Detrusor |
|
| consists of patients with normal detrusor (bladder contractility index more than 100). | Active Comparator | • Group (A) - Normal detrusor |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| transurethral resection of Prostate | Procedure | Standard TURP |
|
| Measure | Description | Time Frame |
|---|---|---|
| Restore spontaneous voiding | All the included patients in this study are urethral catheter-dependant pre-operatively and have very bad voiding parameters. we will assess how they will benefit after TURP by regaining spontaneous voiding without the need for urethral catheters any more. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Flow rate improvement | uroflowmetry will be done to all patients 3 months post operative and results will be compared | 3 months |
| Post voiding residual urine volume decrease | Post voiding residual urine volume will be calculated using ultrasound and results will be compared |
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Inclusion Criteria:
Exclusion Criteria:
Male
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Samir Sherif Rizkallah, MBBCH | Contact | +201226846005 | 150278@med.asu.edu.eg |
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| ID | Type | URL | Comment |
|---|---|---|---|
| 33645847 | Clinical Study Report | View IPD |
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| 3 months |
| 24184024 | Clinical Study Report | View IPD |
| ID | Term |
|---|---|
| D000077295 | Urinary Bladder, Underactive |
| ID | Term |
|---|---|
| D001745 | Urinary Bladder Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D020728 | Transurethral Resection of Prostate |
| ID | Term |
|---|---|
| D011468 | Prostatectomy |
| D013521 | Urologic Surgical Procedures, Male |
| D013520 | Urologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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