COMPARISON OF DEXMEDETOMIDINE AND NORMAL SALINE IN NEBULIZATION TO BLUNT HEMODYNAMIC RESPONSE

Comparison of Nebulised Dexmedetomidine Versus Nebulised Saline Preoperatively To Attenuate Hemodynamic Response to Laryngoscopy and Endotracheal Intubation: A Randomised Control Trial

BLUNTING OF HEMODYNAMIC RESPONSE WILL BE OBSERVED IN PATIENTS NEBULISED WITH DEXMEDETOMIDINE AND NORMAL SALINE.

ONE GROUP OF PTS WILL BE NEBULISED WITH DEXMEDETOMIDINE AND OTHER WITH NORMAL SALINE AND WILL BE OBSERVED DURING AND AFTER INTUBATION FOR ATTENUATION OF HEMODYNAMIC RESPONSE FOR LYRANGOSCOPY AND ENDOTRACHEAL INTUBATION

Inclusion Criteria:

1. Age 18-60 years
2. Either gender
3. ASA Physical Status I and II
4. Mallampati airway class I and II
5. BMI 18-30 kg/m2
6. Patients undergoing elective surgery under general anesthesia

Exclusion Criteria:

1. Patient refusal or lack of consent
2. Anticipated difficult airway
3. Intubation attempt lasting more than 15 seconds
4. Pregnancy
5. Uncontrolled hypertension, cardiac, pulmonary, hepatic, or cerebral events
6. Known allergy to dexmedetomidine or study drugs