Effects of Different Tunnel Methods in PICC Catheterization

Effects of Different Tunnel Methods in PICC Catheterization: A Randomized Controlled Trial

This prospective randomized controlled trial compares the effectiveness and safety of one-needle and two-needle tunneling techniques for peripherally inserted central catheter (PICC) placement, aiming to identify the optimal tunneling method to reduce catheter-related complications.

Inclusion Criteria:

• Aged between 18 and 75 years old;
• Educational level of primary school or above, with basic listening, speaking, reading and writing abilities, and capable of completing the questionnaire independently;
• Receiving tunneled PICC catheterization for the first time, with 4Fr single-lumen solo PICC catheter indwelling;
• Able to attend regular PICC maintenance at our hospital as scheduled after catheterization;
• Voluntarily participate in this study and sign the informed consent form for this study as well as the informed consent form for PICC catheterization.

Exclusion Criteria:

• Patients with coagulation dysfunction (INR > 1.5 / PLT < 50×10⁹/L);
• Pregnant or lactating women;
• Patients with BMI < 18.5 kg/m²;
• Patients receiving PICC catheterization via lower extremity veins;
• Patients with known or suspected allergy to components of PICC catheters.