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This study aims to provide evidence on the optimal timing and efficacy of lacrimal probing in infants with congenital NLDO to minimize morbidity and healthcare costs .
Congenital nasolacrimal duct obstruction (CNLDO) manifests with symptoms such as excessive tearing, lash crusting, and mucopurulent secretions. A significant cohort study revealed that CNLDO affects one in nine newborns, highighting its public health significance 1.
Controversies per-sist regarding the most appropriate time and type of intervention for managing CNLDO2 .
Standard early management typically includes hydrostatic lacrimal sac massage combined with topical antibiotics. Many ophthalmologists believe that a majority of obstructions resolve spontaneously with massage; however, around 25% of children may require additional intervention such as probing 3.
Currently, there is no established consensus on the optimal timing for intervention in theses cases. Because of the possibility of spontaneous resolution, some authors recommend postponing probing until after one year of age . Conversely, other studies suggest that delaying probing beyond six months may increase the risk of inflammation and fibrosis, potentially lowering the success rates of later interventions 4.
Aim of the study This study aims to provide evidence on the optimal timing and efficacy of lacrimal probing in infants with congenital NLDO to minimize morbidity and healthcare costs .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| early probing | Experimental | patients with congenital nasolacrimal duct obstruction will undergo early probing |
|
| massage | No Intervention | patients with congenital nasolacrimal duct obstruction will undergo lacrimal massage |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| naslacrimal duct probing | Procedure | nasolacrimal duct probing |
|
| Measure | Description | Time Frame |
|---|---|---|
| epiphora stop evaluated by Munk scale and TEARS scale | Munk Scale, which ranges from 0 (no tearing) to 5 (constant tearing) based on daily wiping frequency. TEARS Scale, which measures four subscales: Times of wiping, Effects (clinical), Activity limitations, and Reflex tearing. | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hany Mahmoud | Contact | 01024368111 | drhanymahmoud@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Hany Mahmoud | Sohag University | Study Director |
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data are available upon request
3 months
all
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| ID | Term |
|---|---|
| D007767 | Lacrimal Duct Obstruction |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
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randomized clinical trial
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double blind