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The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| GENERAL ANESTHESIA | Active Comparator | THIS GROUP WILL INCLUDE PATIENTS WHO ARE UNDER GENERAL ANESTHESIA. |
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| cervical plexus block | Active Comparator | IN THIS GROUP, CERVICAL PLEXUS BLOCK WILL BE PERFORMED IN ADDITION TO GENERAL ANESTHESIA. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| General Anesthesia | Procedure | In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block. The inflammatory response is a natural response of the body's immune system to surgical trauma, and it can vary depending on the anesthetic agent used. In regulating this response, molecules such as IL-1β, TNF-α, IL-6, IL-10, and IL-40 are important indicators that determine the severity and duration of inflammation. These parameters will be examined and compared in both groups. |
| Measure | Description | Time Frame |
|---|---|---|
| Perioperative Inflammatory Response | IL-1β, TNF-α, IL-6, IL-10, and IL-40 levels will be measured 1 hour before surgery, and then 2 and 6 hours after surgery, and these values will then be compared. | Before the procedure, and at 2 and 6 hours after the procedure. |
| Inflammatory Response | IL-1β, TNF-α, IL-6, IL-10, and IL-40 levels will be measured 1 hour before surgery, and then 2 and 6 hours after surgery, and these values will then be compared. | Before the procedure, and at 2 and 6 hours after the procedure. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Abdulhakim Åžengel | Contact | +905374030916 | ahsengel121@gmail.com |
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| ID | Term |
|---|---|
| D000768 | Anesthesia, General |
| D066008 | Cervical Plexus Block |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
| D009407 | Nerve Block |
| D000765 | Anesthesia, Conduction |
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| cervical plexus block | Procedure | In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block. |
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