Frozen Section Examination of Sentinel Lymph Nodes in Breast Cancer

Frozen Section Examination of Sentinel Lymph Nodes in Breast Cancer: A Prospective Randomized Clinical Study

This prospective randomized clinical study evaluates the role of intraoperative frozen section examination of sentinel lymph nodes in patients with breast cancer. The study aims to determine whether frozen section assessment during surgery improves intraoperative decision-making and affects surgical management when compared with standard final pathological evaluation performed after surgery.

Inclusion Criteria:

• Patients diagnosed with breast carcinoma
• No prior neoadjuvant treatment

Exclusion Criteria:

• Inability to localize the sentinel lymph node preoperatively by lymphoscintigraphy or blue dye
• Previous axillary surgery
• Recurrent breast cancer
• Patients who cannot receive radiotherapy
• Prior neoadjuvant treatment