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| Name | Class |
|---|---|
| Prince Sattam Bin Abdulaziz University | OTHER |
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Pediatric burn survivors may experience persistent deficits in lower-limb strength, explosive power, and functional performance after hospital discharge. This randomized controlled trial evaluated whether a 12-week supervised plyometric training program improves lower-extremity muscle strength, power, and functional capacity compared with a standard exercise program in children and adolescents with severe burn injuries.
This two-arm, parallel-group, single-blind randomized controlled trial included 62 pediatric burn survivors aged 10-18 years with severe burns involving ≥30% total body surface area and lower-limb involvement. Participants were recruited 6-12 months after hospital discharge and randomly allocated in a 1:1 ratio to either plyometric training or standard exercise.
Both groups received supervised exercise twice weekly for 12 weeks. The experimental group completed progressive plyometric exercises designed to enhance lower-extremity explosive power and dynamic functional mobility. The control group received standard post-discharge rehabilitation focused on flexibility, aerobic conditioning, mobility, and basic strengthening. Outcomes were assessed at baseline and immediately after the 12-week intervention by blinded assessors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Plyometric Training Group | Experimental | Participants received a 12-week supervised plyometric training program, twice weekly, with each session lasting 45 minutes. Sessions included dynamic warm-up, progressive plyometric exercises targeting vertical and horizontal force production, and cool-down. |
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| Standard Exercise Group | Active Comparator | Participants received a 12-week supervised standard exercise program, twice weekly, with each session lasting 45 minutes. Sessions focused on flexibility, aerobic conditioning, mobility, and basic lower-limb strengthening. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plyometric Training | Other | Participants in the plyometric training group will receive a 12-week supervised program, with each session lasting 45 minutes and designed to improve lower-extremity explosive power and dynamic functional mobility. Sessions will include a 5-minute dynamic warm-up, 35 minutes of progressive plyometric exercises targeting vertical and horizontal force production, and a 5-minute cool-down. Training will be individually supervised with safety measures including shock-absorbing flooring, cushioned footwear, technique monitoring, and standardized rest intervals. |
| Measure | Description | Time Frame |
|---|---|---|
| Lower-Limb Muscle Strength | Quadriceps and hamstring strength will be assessed using an isokinetic dynamometer. After standardized positioning, stabilization, warm-up, and familiarization, participants will perform five maximal reciprocal knee extension/flexion repetitions. The highest peak torque value (Nm) for hamstrings and quadriceps will be recorded. | pre-intervention (Week 0) |
| Lower-Limb Muscle Strength | Quadriceps and hamstring strength will be assessed using an isokinetic dynamometer. After standardized positioning, stabilization, warm-up, and familiarization, participants will perform five maximal reciprocal knee extension/flexion repetitions. The highest peak torque value (Nm) for hamstrings and quadriceps will be recorded. | immediately post-intervention (Week 12) |
| Measure | Description | Time Frame |
|---|---|---|
| Vertical Jump Height | Vertical Jump Test: Lower-limb explosive power will be assessed using a vertical jump performed on a force plate. Participants will jump maximally with hands on hips to minimize arm contribution, completing three trials with 60 seconds of rest between trials. The highest jump height will be recorded in centimeters. | pre-intervention (Week 0) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Maged A Basha, PhD | Qassim University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Prince Sattam bin Abdulaziz University | Al Kharj | Saudi Arabia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29596648 | Background | Rivas E, Herndon DN, Cambiaso-Daniel J, Rontoyanni VG, Porter C, Glover S, Suman OE. Quantification of an Exercise Rehabilitation Program for Severely Burned Children: The Standard of Care at Shriners Hospitals for Children(R)-Galveston. J Burn Care Res. 2018 Oct 23;39(6):889-896. doi: 10.1093/jbcr/iry001. | |
| 41283468 | Background |
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De-identified individual participant data supporting the published results will be available from the corresponding author upon reasonable request.
6 months after publication
Requests will be reviewed for scientific relevance, methodological quality, and approval by all co-authors. Data will be shared after approval and, if required, completion of a data-sharing agreement.
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| ID | Term |
|---|---|
| D002056 | Burns |
| D018908 | Muscle Weakness |
| ID | Term |
|---|---|
| D014947 | Wounds and Injuries |
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D020879 | Neuromuscular Manifestations |
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| ID | Term |
|---|---|
| D059385 | Plyometric Exercise |
| ID | Term |
|---|---|
| D005081 | Exercise Therapy |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
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Participants were randomized 1:1 to plyometric training or standard exercise for 12 weeks. Outcome assessors were blinded to group allocation.
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| Standard Exercise Program | Other | Participants in the control group will receive a 12-week supervised program, with each session lasting 45 minutes post-discharge burn rehabilitation program focusing on mobility, flexibility, aerobic conditioning, and basic lower-limb strengthening. Sessions will include warm-up, stretching, moderate-intensity aerobic exercise at 50-70% of age-predicted maximum heart rate, strengthening exercises, and cool-down, with progression based on participant tolerance. |
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| Vertical Jump Height | Vertical Jump Test: Lower-limb explosive power will be assessed using a vertical jump performed on a force plate. Participants will jump maximally with hands on hips to minimize arm contribution, completing three trials with 60 seconds of rest between trials. The highest jump height will be recorded in centimeters. | immediately post-intervention (Week 12) |
| Broad Jump Distance | Horizontal lower-limb power and dynamic leg strength will be assessed using the broad jump test. Participants will perform three maximal two-footed forward jumps from a marked starting line, with 60 seconds of rest between trials. The longest distance, measured from the starting line to the rearmost landing point, will be recorded in centimeters. | pre-intervention (Week 0) |
| Broad Jump Distance | Horizontal lower-limb power and dynamic leg strength will be assessed using the broad jump test. Participants will perform three maximal two-footed forward jumps from a marked starting line, with 60 seconds of rest between trials. The longest distance, measured from the starting line to the rearmost landing point, will be recorded in centimeters. | immediately post-intervention (Week 12) |
| Reactive Strength Index | Reactive strength will be assessed using a drop jump from a 30-cm box onto a force plate. Three trials will be performed with 60 seconds of rest, and the highest reactive strength index value, calculated as jump height divided by ground contact time, will be recorded. | pre-intervention (Week 0) |
| Reactive Strength Index | Reactive strength will be assessed using a drop jump from a 30-cm box onto a force plate. Three trials will be performed with 60 seconds of rest, and the highest reactive strength index value, calculated as jump height divided by ground contact time, will be recorded. | immediately post-intervention (Week 12) |
| Lower Extremity Functional Scale Score | Lower-limb functional ability will be assessed using the 20-item Lower Extremity Functional Scale, which evaluates perceived difficulty in activities such as walking, running, stair climbing, and squatting. Each item is scored from 0 to 4, with a total score ranging from 0 to 80. Higher scores indicate better functional capacity. | pre-intervention (Week 0) |
| Lower Extremity Functional Scale Score | Lower-limb functional ability will be assessed using the 20-item Lower Extremity Functional Scale, which evaluates perceived difficulty in activities such as walking, running, stair climbing, and squatting. Each item is scored from 0 to 4, with a total score ranging from 0 to 80. Higher scores indicate better functional capacity. | immediately post-intervention (Week 12) |
| Six-Minute Walk Test Distance | Functional exercise capacity will be assessed using the Six-Minute Walk Test performed along a 30-meter indoor corridor according to standardized guidelines. Participants will be instructed to walk as far as possible, without running, within six minutes, and the total distance covered will be recorded in meters. | pre-intervention (Week 0) |
| Six-Minute Walk Test Distance | Functional exercise capacity will be assessed using the Six-Minute Walk Test performed along a 30-meter indoor corridor according to standardized guidelines. Participants will be instructed to walk as far as possible, without running, within six minutes, and the total distance covered will be recorded in meters. | immediately post-intervention (Week 12) |
| Timed Up and Down Stairs Performance | Lower-limb power, agility, and dynamic balance will be assessed using the Timed Up and Down Stairs test. Participants will ascend and descend 10 standard stairs as quickly and safely as possible, with two trials performed and the fastest time recorded in seconds. | pre-intervention (Week 0) |
| Timed Up and Down Stairs Performance | Lower-limb power, agility, and dynamic balance will be assessed using the Timed Up and Down Stairs test. Participants will ascend and descend 10 standard stairs as quickly and safely as possible, with two trials performed and the fastest time recorded in seconds. | immediately post-intervention (Week 12) |
| 4×10-Meter Shuttle Run Time | Agility and speed will be assessed using the 4×10-meter shuttle run test. Participants will run back and forth between two cones placed 10 meters apart, completing four 10-meter segments for a total distance of 40 meters. Two trials will be performed, and the fastest completion time will be recorded in seconds. | pre-intervention (Week 0) |
| 4×10-Meter Shuttle Run Time | Agility and speed will be assessed using the 4×10-meter shuttle run test. Participants will run back and forth between two cones placed 10 meters apart, completing four 10-meter segments for a total distance of 40 meters. Two trials will be performed, and the fastest completion time will be recorded in seconds. | immediately post-intervention (Week 12) |
| Figure-of-8 Walk/Run Test Time | Dynamic balance, agility, and coordination will be assessed using the Figure-of-8 Walk/Run Test. Participants will complete two full loops around two cones placed 5 meters apart as quickly as possible. Two trials will be performed, and the fastest completion time will be recorded in seconds. | pre-intervention (Week 0) |
| Figure-of-8 Walk/Run Test Time | Dynamic balance, agility, and coordination will be assessed using the Figure-of-8 Walk/Run Test. Participants will complete two full loops around two cones placed 5 meters apart as quickly as possible. Two trials will be performed, and the fastest completion time will be recorded in seconds. | immediately post-intervention (Week 12) |
| Neriamparambil AJ, Sawhney R, Wong WL. Evidence-Based Management of Burns: A Narrative Review of Evolving Practices. Eur Burn J. 2025 Nov 10;6(4):59. doi: 10.3390/ebj6040059. |
| 34016485 | Result | Elnaggar RK, Osailan AM, Alsubaie SF, Moawd SA, Abd El-Nabie WA. Graded aerobic exercise (GAEx): An effective exercise regimen to improve cardio-respiratory fitness and physical and psychosocial functioning in children with burn sequelae of the chest. Burns. 2022 Mar;48(2):337-344. doi: 10.1016/j.burns.2021.05.004. Epub 2021 May 13. |
| 33909503 | Result | Knuth CM, Auger C, Jeschke MG. Burn-induced hypermetabolism and skeletal muscle dysfunction. Am J Physiol Cell Physiol. 2021 Jul 1;321(1):C58-C71. doi: 10.1152/ajpcell.00106.2021. Epub 2021 Apr 28. |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |
| D005791 |
| Patient Care |
| D013812 | Therapeutics |
| D026741 | Physical Therapy Modalities |
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |