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This study aims to better quantify the improvements in heart failure symptoms and exercise tolerance before and after the heart rate elevation in a cohort of 10 cardiac amyloidosis patients with preexisting pacemakers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Elevated Pacemaker Rate | Experimental | CA clinic patients with pacemakers will receive a personalized pacing protocol individual to their height and left ventricular ejection fraction. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pacemaker Rate | Other | CA clinic patients with pacemakers will receive a personalized pacing protocol individual to their height and left ventricular ejection fraction. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Kansas City Cardiomyopathy Questionnaire Score | 75-100 representing good to excellent health, and 0-24 representing very poor to poor health | Month 4 |
| Composite of any cardiovascular event | admission or urgent visit for heart failure and atrial fibrillation, myocardial infarction or stroke | Month 4 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Meghan Muscala | Contact | 612-626-5863 | payne324@umn.edu |
| Name | Affiliation | Role |
|---|---|---|
| Valmiki Maharaj | University of Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Recruiting | Minneapolis | Minnesota | 55455 | United States |
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| ID | Term |
|---|---|
| D028227 | Amyloid Neuropathies, Familial |
| ID | Term |
|---|---|
| D020271 | Heredodegenerative Disorders, Nervous System |
| D019636 | Neurodegenerative Diseases |
| D009422 | Nervous System Diseases |
| D017772 | Amyloid Neuropathies |
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| D010523 | Peripheral Nervous System Diseases |
| D009468 | Neuromuscular Diseases |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D028226 | Amyloidosis, Familial |
| D008661 | Metabolism, Inborn Errors |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D000686 | Amyloidosis |
| D057165 | Proteostasis Deficiencies |