Prospective Study of High-penetration Super-resolution Transcranial Ultrasound for Early Identification of Postoperative Intracranial Metallic Targets After Aneurysm Clipping

Clinical Model-Based Evaluation of High-Penetration Super-Resolution Transcranial Ultrasound for Early Diagnosis of Intracranial Metallic Foreign Bodies in Patients After Intracranial Aneurysm Clipping

To evaluate the patient-level early diagnostic performance of high-penetration super-resolution transcranial ultrasound for identifying intracranial metallic targets, and to further assess clip-level detection, localization, agreement, and its complementary value to routine postoperative imaging.This study does not alter routine clinical treatment. All participants will undergo standardized high-penetration super-resolution transcranial ultrasound within 3 hours after surgery. Postoperative CT is mandatory for all participants; CTA or other routine postoperative imaging will be obtained only when clinically indicated.

Inclusion Criteria:

1. Age 18-85 years;
2. Positive group: patients undergoing intracranial aneurysm clipping with implanted metallic clips; negative control group: postoperative craniotomy patients without implanted clips;
3. Ability to complete transcranial ultrasound within 3 hours after surgery;
4. Availability of postoperative CT;
5. Written informed consent from the participant or legally authorized representative.

Exclusion Criteria:

1. Inability to complete standardized transcranial ultrasound;
2. Missing postoperative CT;
3. Inability to establish the composite reference standard;
4. Presence of non-study-related metallic materials that may substantially interfere with target identification;
5. Withdrawal of consent;
6. Investigator judgment that continued participation is inappropriate.