Impact of the Procurement Technique on Outcomes After Liver Transplantation

Impact of the Procurement Technique on Outcomes After Liver Transplantation: a French Multicenter Prospective Study

Liver transplantation (LT) is the standard treatment for hepatocellular carcinoma (HCC) and end-stage liver disease, with excellent long-term outcomes despite the increasing use of extended criteria donors due to organ shortage. As traditional evaluation criteria have become insufficient, new indicators such as Arterial and Biliary Complication-Free Survival (ABCFS) have been developed to better assess post-transplant outcomes.

Primary objective: To assess, in a large-scale study, whether the procurement technique influences liver transplantation outcomes in terms of arterial and biliary complication-free survival.

Inclusion Criteria:

1. Patients aged 18 years or older at the time of inclusion
2. Listed on the national waiting list of the Agence de la Biomédecine (ABM)
3. Undergoing a first liver transplantation in France
4. Receiving a whole liver graft
5. No prior or subsequent transplantation of another organ

Exclusion Criteria:

1. Pancreas procurement
2. Multiorgan transplantation
3. Split liver transplantation (shared grafts)
4. Retransplantation
5. Domino transplantation (no actual organ procurement in the conventional sense)
6. Patient refusal to allow the use of their data