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Liver transplantation (LT) is the standard treatment for hepatocellular carcinoma (HCC) and end-stage liver disease, with excellent long-term outcomes despite the increasing use of extended criteria donors due to organ shortage. As traditional evaluation criteria have become insufficient, new indicators such as Arterial and Biliary Complication-Free Survival (ABCFS) have been developed to better assess post-transplant outcomes.
Primary objective: To assess, in a large-scale study, whether the procurement technique influences liver transplantation outcomes in terms of arterial and biliary complication-free survival.
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| Measure | Description | Time Frame |
|---|---|---|
| Arterial and Biliary Complication-Free Survival (ABCFS) at 3 years | at 3 years post-transplantation |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative complications at 90 days | at 90 days post-transplantation | |
| Type of Biliary complications | Up to 3 years post-transplantation | |
| Type of Arterial complications |
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Inclusion Criteria:
Exclusion Criteria:
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adult patients (≥18 years) who undergo a first liver transplantation in France.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eric Savier, MD, PhD | Contact | +33 1 42 17 56 90 | eric.savier@aphp.fr | |
| Jinmi BAEK | Contact | jinmi.baek@aphp.fr |
| Name | Affiliation | Role |
|---|---|---|
| Astrid HERRERO, MD, PhD | Saint Eloi Hospital, Montpellier University Hospital | Study Chair |
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| ID | Term |
|---|---|
| D006528 | Carcinoma, Hepatocellular |
| ID | Term |
|---|---|
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
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| Up to 3 years post-transplantation |
| Occurrence of vascular injuries observed following organ procurement | Peri-procedural period (during procurement and immediately post-procurement) |
| Rehospitalization Rate Post-LT | Number of rehospitalizations per patient occurring after the initial transplantation hospitalization. | Up to 3 years post-transplantation |
| Duration of Rehospitalizations Post-LT | Length of stay for each rehospitalization occurring after the initial transplantation hospitalization. | Up to 3 years post-transplantation |
| Reasons for Rehospitalizations Post-LT | Reason for each rehospitalization occurring after the initial transplantation hospitalization, categorized by diagnosis. | Up to 3 years post-transplantation |
| D009369 | Neoplasms |
| D008113 | Liver Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D004066 | Digestive System Diseases |
| D008107 | Liver Diseases |