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This randomized controlled study to examine the efficacy of ER class in cancer survivors with chronic pain. Eligible participants will be randomly assigned to a ER class or a waitlist control condition. We will recruit 250 participants with a goal of having 200 completers (20% attrition). Participants in the control condition will be invited to attend ER class after the 3-month observation period.
The Empowered Relief (ER) study is a Zoom-based, 1-session, 2-hour, skills-based pain management class delivered by certified instructors. Participants learn three core pain relief skills, develop a personalized plan, and receive access to a free binaural audio app for daily use and supportive daily text messages. Participants will fill out a series of follow-up surveys at the 1, 2, and 3-month post-class mark. These surveys will be directly compared to surveys given to participants that do not complete the course. Class admittance will be randomized, however, participants not in the treatment group will have the option to take the course after the 3-month observatory period. ER has demonstrated moderate efficacy in individuals with chronic non-cancer pain, reducing pain intensity, pain interference, pain-related distress (pain catastrophizing), sleep disturbance, and anxiety. Because of its brief, didactic nature and delivery via Zoom, ER can accommodate large class sizes and may address access disparities among underserved cancer survivors. ER is currently being studied across various non-cancer populations and has been adopted as standard of care in leading healthcare institutions in the U.S. and abroad. Yet, Empowered Relief has not been tested in cancer survivors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Empowered Relief | Experimental | Participants in this arm of the study will complete the one-time 2hr Empowered Relief zoom course. They will also complete a post-course survey as well as the standardized 1, 2, and 3-month follow-up surveys. |
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| Wait-List Control | No Intervention | Participants in the Wait-List Control (WLC) arm will not have initial access to the empowered relief course. Additionally they will not have to complete a post-course survey. The WLC group will be asked to complete the 1, 2, and 3-month follow-up studies after no intervention. After this 3-month observatory period, WLC participants will have voluntary access to the Empowered Relief course. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Empowered Relief Course (Zoom) | Behavioral | This is a one-time 2 hour long skills-based pain management class delivered by certified instructors. Participants learn three core pain relief skills, develop a personalized plan, and receive access to a free binaural audio app for daily use and supportive daily text messages. |
| Measure | Description | Time Frame |
|---|---|---|
| Overall treatment satisfaction | 0-10 scale, higher scores indicate greater satisfaction, mean should be 8 or higher | Immediately after intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Pain Intensity | 0-10 scale, higher scores indicate higher pain | 1 month after intervention |
| Pain Interference | T-scores, higher scores indicate higher pain interference |
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Inclusion Criteria:
History of cancer diagnosis, completion of active cancer treatment, cancer free at the time of enrollment, experience of body pain most or every day, pain duration at least 3 months, and English fluency.
Exclusion Criteria:
Significant psychological and cognitive impairment that limits one's ability to complete study tasks (completion of online survey, attending the zoom-based ER class). Life-threatening acute illness (e.g., infection, heart attack, injury), and no access to a computer, a smartphone or a tablet.
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sophia You, PhD, ABPP | Contact | 918-660-3923 | Dokyoung-You@ou.edu | |
| Jordan Keast, BS | Contact | jordan-keast@ou.edu |
| Name | Affiliation | Role |
|---|---|---|
| Sophia You, PhD, ABPP | University of Oklahoma | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Oklahoma Schusterman Center - Tulsa | Recruiting | Tulsa | Oklahoma | 74135 | United States |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Apr 17, 2026 | Apr 28, 2026 | Prot_SAP_000.pdf |
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| ID | Term |
|---|---|
| D059350 | Chronic Pain |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| 1 month after intervention |
| Pain Intensity | 0-10 Scale, higher scores indicate higher pain | 3 months after intervention |
| Pain Interference | T-scores, higher scores indicate higher pain interference | 3 months after intervention |