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This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan. The registry focuses on process quality indicators, including first-pass success, and patient-safety outcomes, including hypoxemia, hypotension, and peri-intubation cardiac arrest within 30 minutes of intubation. Routinely generated laboratory and physiologic variables are also collected to improve risk stratification and identify predictors of major adverse events. The study is non-interventional and does not alter clinical care.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Adult patients in ED require emergent tracheal intubation |
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of major adverse peri-intubation events within 30 minutes after the start of intubation | severe hypoxemia, severe hypotension/cardiovascular instability, or cardiac arrest. | Periprocedural, through 30 minutes after the start of intubation |
| Measure | Description | Time Frame |
|---|---|---|
| First-pass success | Periprocedural | |
| In-hospital mortality | From intubation to hospital discharge, assessed up to 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| Pre-intubation severe metabolic acidosis | Within 2 hours before the start of intubation |
Inclusion Criteria:
Exclusion Criteria:
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Consecutive adult emergency department patients undergoing tracheal intubation at participating hospitals in Taiwan.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| TING HAO YANG, Doctor | Contact | +886978989007 | mr2434@cgmh.org.tw |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| New Taipei Municipal Tucheng Hospital, New Taipei City, Taiwan | New Taipei City | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41094343 | Background | Garcia SI, Smischney NJ, Sandefur BJ, D'Andria Ursoleo J, Kelm DJ, Wieruszewski PM. Peri-intubation Cardiovascular Collapse During Emergency Airway Management. Pulm Ther. 2025 Dec;11(4):569-585. doi: 10.1007/s41030-025-00326-x. Epub 2025 Oct 16. | |
| 22155701 | Background | Hasegawa K, Hagiwara Y, Chiba T, Watase H, Walls RM, Brown DF, Brown CA 3rd; Japanese Emergency Medicine Research Alliance. Emergency airway management in Japan: Interim analysis of a multi-center prospective observational study. Resuscitation. 2012 Apr;83(4):428-33. doi: 10.1016/j.resuscitation.2011.11.027. Epub 2011 Dec 8. |
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De-identified data will be retained under institutional governance and are not currently planned for public individual participant data sharing.
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | Apr 28, 2026 | Apr 27, 2026 | Prot_SAP_000.pdf |
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| ID | Term |
|---|---|
| D004630 | Emergencies |
| D000860 | Hypoxia |
| D007022 | Hypotension |
| D006323 | Heart Arrest |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012818 | Signs and Symptoms, Respiratory |
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| 40247381 | Background | Maia IWA, Besen BAMP, Silva LOJE, von Hellmann R, Hajjar LA, Sandefur BJ, Pedrollo DF, Nogueira CG, Figueiredo NMP, Miranda CH, Martins D, Baumgratz TD, Bergesch B, Costa D, Colleoni O, Zanettini J, Freitas AP, Moreira NP, Gaspar PL, Tambelli R, Costa MC, Silveira S, Correia W, de Maria RG, Filho UAV, Weber AP, da Silva Castro V, Dornelles CFD, Tabach BS, Guimaraes HP, Stanzani G, Gava TF, Mullan A, Souza HP, Ranzani OT, Bellolio F, Alencar JCG; BARCO group. Peri-intubation adverse events and clinical outcomes in emergency department patients: the BARCO study. Crit Care. 2025 Apr 17;29(1):155. doi: 10.1186/s13054-025-05392-w. |
| 24099373 | Background | Cho J, Cho YS, You JS, Lee HS, Kim H, Chung HS; Korean Emergency Airway Management Society. Current status of emergency airway management for elderly patients in Korea: Multicentre study using the Korean Emergency Airway Management Registry. Emerg Med Australas. 2013 Oct;25(5):439-44. doi: 10.1111/1742-6723.12122. Epub 2013 Sep 9. |
| 33684505 | Background | April MD, Arana A, Reynolds JC, Carlson JN, Davis WT, Schauer SG, Oliver JJ, Summers SM, Long B, Walls RM, Brown CA 3rd; NEAR Investigators. Peri-intubation cardiac arrest in the Emergency Department: A National Emergency Airway Registry (NEAR) study. Resuscitation. 2021 May;162:403-411. doi: 10.1016/j.resuscitation.2021.02.039. Epub 2021 Mar 5. |
| 28582801 | Background | Alkhouri H, Vassiliadis J, Murray M, Mackenzie J, Tzannes A, McCarthy S, Fogg T. Emergency airway management in Australian and New Zealand emergency departments: A multicentre descriptive study of 3710 emergency intubations. Emerg Med Australas. 2017 Oct;29(5):499-508. doi: 10.1111/1742-6723.12815. Epub 2017 Jun 5. |
| 33755076 | Background | Russotto V, Myatra SN, Laffey JG, Tassistro E, Antolini L, Bauer P, Lascarrou JB, Szuldrzynski K, Camporota L, Pelosi P, Sorbello M, Higgs A, Greif R, Putensen C, Agvald-Ohman C, Chalkias A, Bokums K, Brewster D, Rossi E, Fumagalli R, Pesenti A, Foti G, Bellani G; INTUBE Study Investigators. Intubation Practices and Adverse Peri-intubation Events in Critically Ill Patients From 29 Countries. JAMA. 2021 Mar 23;325(12):1164-1172. doi: 10.1001/jama.2021.1727. |
| D012816 | Signs and Symptoms |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |