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| Name | Class |
|---|---|
| Siping Central People's Hospital | OTHER |
| Baicheng Central Hospital | UNKNOWN |
| Jilin Central General Hospital | UNKNOWN |
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This study plans to find the most suitable lymph node cortex thickness and abnormal lymph node features to define suspicious lymph nodes. Then, ultrasound-guided core needle biopsy of axillary lymph nodes will be done, aiming to provide some guidance for the biopsy.
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| Measure | Description | Time Frame |
|---|---|---|
| Maximum cortical thickness of the lymph node (mm) | The maximum thickness of the lymph node's cortical layer. Measured via conventional ultrasound examination of the lymph node's long-axis cross-section, perpendicular to the capsule surface, determining the maximum distance from the capsule to the corticomedullary junction. | Measurements should be performed prior to treatment initiation, with a time interval not exceeding 4 weeks between the measurement and pathological examination. |
| Measure | Description | Time Frame |
|---|---|---|
| Age | Age of participants at the time of initial diagnosis of primary breast cancer, reported in years. | Baseline |
| Menstrual Status | Menstrual status at initial diagnosis of primary breast cancer, assessed by medical record review and categorized as premenopausal, perimenopausal, postmenopausal, or unknown. |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive patients newly diagnosed with primary breast cancer and assessed for axillary lymph node metastasis by ultrasound, prospectively enrolled from November 2025 to November 2026 across multiple hospitals.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dezhi Zhang | Contact | 18186876068 | dezhi@jlu.edu.cn |
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| ID | Term |
|---|---|
| D008207 | Lymphatic Metastasis |
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009362 | Neoplasm Metastasis |
| D009385 | Neoplastic Processes |
| D009369 | Neoplasms |
| D010335 | Pathologic Processes |
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| At initial diagnosis of primary breast cancer |
| Lymph node axial ratio | The ratio of the maximum longitudinal diameter to the maximum transverse diameter of the lymph node. The maximum longitudinal diameter and maximum transverse diameter of the lymph node are measured separately, and the axial ratio is obtained by dividing the measured longitudinal diameter value by the transverse diameter value. | Measurements should be performed prior to treatment initiation, with a time interval not exceeding 4 weeks between the measurement and pathological examination. |
| Lymph node margin regularity | Categorized as either regular or irregular. | Measurements should be performed prior to treatment initiation, with a time interval not exceeding 4 weeks between the measurement and pathological examination. |
| Lymph node hilum type | Lymph node hilum type assessed on pre-treatment imaging, categorized according to the presence or absence of the lymph node hilum. | Within 4 weeks before pathological examination and prior to treatment initiation |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D009371 | Neoplasms by Site |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |