Proof of Concept for Simulating Static Weight-bearing Exercises in the Supine Position

Validation and Evaluation of a Static Supine Weight-Bearing Computed Tomography Method to Enable Detection of Implant Migration After Knee Arthroplasty

This project evaluates a new weight-bearing CT method to later improve early detection of implant migration after knee arthroplasty.

This method aims to allow patients to apply a controlled load during CT scanning, simulating standing conditions with real-time feedback.

The study has two phases. First, in healthy volunteers, biomechanical loading during prone simulated weight-bearing will be compared with a standard standing squat to validate the method. Second, in arthroplasty patients, standard radiographs will be compared with loaded and unloaded WBCT scans.

Patients will not deviate from the standard plan of care. The CT images are additions to the standard RX images and are not intended for diagnostic purposes to the patient.

The aim is to determine whether this method opens the door for more accurate and earlier detection of implant migration than current clinical imaging in the future, potentially improving long-term outcomes after knee arthroplasty.

Inclusion Criteria:

• Healthy participants
• Patients with TKA

Exclusion Criteria:

• neurological conditions
• acute trauma