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The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone. For this purpose, anesthesiologists use so called objective neurlmuscular monitors. These monitors stimulate the ulnar nerve in the wrist and examine the evoked muscle response. The aim of this study is to examine the usability of another nerve in the wrist, the median nerve.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Median nerve examination | Median nerves in the dominant and non-dominant hands are are examined |
| |
| Ulnar nerve examination | Ulnar nerves in the dominant and non-dominant hands are examined |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electromyography | Diagnostic Test | Electromyographic examination of the median and ulnar nerves to monitor intraoperative neuromuscular blockade |
|
| Measure | Description | Time Frame |
|---|---|---|
| CMAP | Comparison of compound muscle action potential amplitudes evoked by median and ulnar nerve stimulation and measured at the thenar | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Recovery time | Time from muscle relaxant administration to spontaneous recovery to TOFR>0,9 monitored with median and ulnar nerve stimulation | Perioperative |
| Onset time | Time from administration of muscle relaxant to disappearance of twitch response (TOFC0) monitored with median and ulnar nerve stimulation |
| Measure | Description | Time Frame |
|---|---|---|
| Bland-Altman analysis of TOFRs | Bland-Altman analysis of TOFRs obtained with medin and ulnar nerve stimulation | Intraoperative |
| Bland-Altman analysis of TOFCs | Bland-Altman analysis of TOFCs obtained with median and ulnar nerve stimulation |
Inclusion Criteria:
Exclusion Criteria:
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Adult patients undergoing elective surgery that requires one dose of non-depolarising neuromuscular blocking agent, whose arms are accessible for intraoperative neuromuscular blockade monitoring.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Reka Nemes, MD PhD | Contact | +36 30 966 8722 | nemes.reka@med.unideb.hu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Debrecen Medical Center, Department of Anesthesiology and Intensive Care | Recruiting | Debrecen | 4032 | Hungary |
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| ID | Term |
|---|---|
| D004576 | Electromyography |
| ID | Term |
|---|---|
| D004568 | Electrodiagnosis |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D009213 | Myography |
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| Baseline |
| Intraoperative |
| Bland-Altman analysis of PTCs | Bland-Altman analysis of PTCs obtained with median and ulnar nerve stimulation | Intraoperative |
| Baseline TOFRs | Examination of the stability of baseline TOFRs obtained with median and ulnar nerve stabilization | Baseline |
| Comparison of CMAP amplitudes obtained from dominant and non dominant hands | Comparison of CMAP amplitudes obtained from dominant and non dominant hands evoked my median and ulnar nerve stimulation | Baseline |