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| ID | Type | Description | Link |
|---|---|---|---|
| NTUS | Other Identifier | National Taiwan University of Sport |
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The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.
14 healthy adult male active-duty firefighters as participants and used a crossover double-blind design, dividing them into a CAF trial and a PL trial. On the first day of the experiment, after the participants had taken sufficient time off and had a full night's sleep, they rested for 3 hours after dinner on the second day. Following the collection of saliva samples, baseline heart rate variability and firefighting ability tests were conducted. After the tests, the participants ingested 800 mg of GABA and rested for 30 minutes. After that, the participants chewed caffeinated gum containing 3 mg/kg (CAF trial) or caffeine-free placebo gum (PL trial) for 10 minutes, spit it out, rested for 15 minutes. The participants underwent eight firefighting balance tests, during which heart rate variability was measured. After the tests were completed, saliva samples were collected again.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| intervention | Active Comparator | Chewing caffeine gum for 10 minutes |
|
| placebo | Placebo Comparator | Chewing placebo gum for 10 minutes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Caffeine (300 mg) | Dietary Supplement | The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes. |
|
| Measure | Description | Time Frame |
|---|---|---|
| firefighting balance test | Measure the time it takes to return | 15 minutes after intervention |
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Inclusion Criteria:
Exclusion Criteria:
Only male subjects
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| Name | Affiliation | Role |
|---|---|---|
| Chih Hui Chiu | National Taiwan University of Sport | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Taiwan University of Sport | Taichung | North | 404 | Taiwan |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot | Yes | No | No | Study Protocol | Apr 27, 2026 | Apr 28, 2026 | Prot_000.pdf |
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| ID | Term |
|---|---|
| D002110 | Caffeine |
| ID | Term |
|---|---|
| D014970 | Xanthines |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011688 | Purinones |
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| Placebo | Other | The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes. |
|
| D011687 |
| Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |