Lay Summary (Simple Explanation)

Atrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries. These scars can affect appearance and confidence, and current treatments may not always give satisfactory results.

This study aims to evaluate a new treatment using exosomes, which are tiny particles naturally released by cells that help in skin repair and regeneration. Researchers will compare the effect of injecting exosomes directly into scars versus injecting a simple saltwater solution (saline), which serves as a control.

Participants will be randomly assigned to receive either exosome injections or saline injections. Neither the patient nor the evaluator may know which treatment is given, to ensure fair comparison.

The goal is to determine whether exosomes can safely and effectively improve the appearance and texture of atrophic scars.

Inclusion Criteria:

Age >18 years

• Either gender
• Scars of any duration
• Multiple scars at one side or both sides of the face.
• Patients are willing to sign written informed consent statements before beginning treatment.

Exclusion Criteria:

• Pregnant females.
• Patients with one scar.
• Hypersensitivity to any of the used treatments.
• Patient with infection at the site of the scar.
• Patients with unrealistic expectations.
• Patient refusing to sign on the consent.