The goal of this trial is to learn if Pregabalin is better than Acetaminophen in pain management of patients with Post-Mastectomy pain Syndrome, which is defined as pain in the scar, chest wall, shoulder after undergoing mastectomy or breast-conservation (BCS). It could be burning, stabbing, shooting pain or pins-and-needle sensation.

Participants will:

• Take their prescribed allotted medicine for 14 days.
• Will visit the clinic at 2 and 6 week interval for assessment.

Inclusion Criteria:

• All diagnosed cases of post mastectomy pain syndrome
• Patients developing radiation dermatitis grade 0 and 1

Exclusion Criteria:

• Patient undergoing toilet mastectomy
• Patient developing radiation dermatitis grade 2, 3 and 4
• Patients with convulsions
• Patients with known pregabalin hypersensitivity (lightheadedness , sedation , double vision ,increase in bodyweight and imbalance)
• Patients with known acetaminophen hypersensitivity (urticaria, bronchospasm, anaphylaxis)
• Patients with renal failure
• Patients with hepatic dysfunction/ hepatic disease
• Patients with prior use of pregabalin due to chronic pain conditions within 3 months
• Pregnant or lactating
• Neuropsychiatric disorders

The person analyzing the data will be blinded to allocation.