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The study aims to find out if a specific blood test, measuring the balance between two hormones (adiponectin and leptin), can predict how much weight a person might lose after sleeve gastrectomy, a surgery for obesity. The investigators want to see if this hormone ratio can help identify who will benefit most from the surgery. If the investigators find that people with a low hormone ratio are less likely to lose weight after surgery, doctors can guide them toward other weight-loss options, like lifestyle changes or different treatments, instead of surgery. This way, patients can get the care that's best for them.
The subject of the research is to investigate whether preoperative adiponectin-leptin ratios are predictive of weight loss in patients undergoing sleeve gastrectomy for morbid obesity. If the study finds the adiponectin-leptin ratio to be a significant predictor of weight loss, individuals with a low preoperative ratio, which are expected to lose less weight following surgery, can be redirected to more suitable treatment options other than sleeve gastrectomy. This will allow patients less likely to benefit from surgery to be guided toward conservative approaches.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sleeve Gastrectomy Patients | Patients who meet inclusion criteria for the study undergoing sleeve gastrectomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Laparoscopic Sleeve Gastrectomy | Procedure | Laparoscopic Sleeve Gastrectomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in body mass index at 8 months | 8 months after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Change in lipid profile at 8 months | 8 months after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patients applying to Başakşehir Çam Sakura City Hospital General Surgery Clinic for bariatric surgery
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Basaksehir Cam and Sakura City Hospital | Istanbul | Basaksehir | 34480 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D009767 | Obesity, Morbid |
| ID | Term |
|---|---|
| D009765 | Obesity |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
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Blood will be centrifuged and serum will be stored separately in eppendorf tubes.
| D009750 |
| Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |